Measured multipoint ultra-high b-value diffusion MRI in the assessment of MRI-detected prostate lesions
Objectives - The aim of this study was to assess quantitative ultra-high b-value (UHB) diffusion magnetic resonance imaging (MRI)-derived parameters in comparison to standard clinical apparent diffusion coefficient (SD-ADC-2b-1000, SD-ADC-2b-1500) for the prediction of clinically significan...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
February 2021
|
| In: |
Investigative radiology
Year: 2021, Jahrgang: 56, Heft: 2, Pages: 94-102 |
| ISSN: | 1536-0210 |
| DOI: | 10.1097/RLI.0000000000000712 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/RLI.0000000000000712 Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/investigativeradiology/Abstract/2021/02000/Measured_Multipoint_Ultra_High_b_Value_Diffusion.4.aspx 
|
| Verfasserangaben: | Tavakoli, Anoshirwan Andrej MD; Kuder, Tristan Anselm PhD; Tichy, Diana PhD; Radtke, Jan Philipp MD; Görtz, Magdalena MD; Schütz, Viktoria MD; Stenzinger, Albrecht MD; Hohenfellner, Markus MD; Schlemmer, Heinz-Peter MD, PhD; Bonekamp, David MD |
MARC
| LEADER | 00000caa a22000002c 4500 | ||
|---|---|---|---|
| 001 | 1751086658 | ||
| 003 | DE-627 | ||
| 005 | 20240412193301.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 210311s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1097/RLI.0000000000000712 |2 doi | |
| 035 | |a (DE-627)1751086658 | ||
| 035 | |a (DE-599)KXP1751086658 | ||
| 035 | |a (OCoLC)1341398326 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Tavakoli, Andrej |d 1987- |e VerfasserIn |0 (DE-588)118568624X |0 (DE-627)1665044403 |4 aut | |
| 245 | 1 | 0 | |a Measured multipoint ultra-high b-value diffusion MRI in the assessment of MRI-detected prostate lesions |c Tavakoli, Anoshirwan Andrej MD; Kuder, Tristan Anselm PhD; Tichy, Diana PhD; Radtke, Jan Philipp MD; Görtz, Magdalena MD; Schütz, Viktoria MD; Stenzinger, Albrecht MD; Hohenfellner, Markus MD; Schlemmer, Heinz-Peter MD, PhD; Bonekamp, David MD |
| 264 | 1 | |c February 2021 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 01.12.2021 | ||
| 520 | |a Objectives - The aim of this study was to assess quantitative ultra-high b-value (UHB) diffusion magnetic resonance imaging (MRI)-derived parameters in comparison to standard clinical apparent diffusion coefficient (SD-ADC-2b-1000, SD-ADC-2b-1500) for the prediction of clinically significant prostate cancer, defined as Gleason Grade Group greater than or equal to 2. - Materials and Methods - Seventy-three patients who underwent 3-T prostate MRI with diffusion-weighted imaging acquired at b = 50/500/1000/1500s/mm2 and b = 100/500/1000/1500/2250/3000/4000 s/mm2 were included. Magnetic resonance lesions were segmented manually on individual sequences, then matched to targeted transrectal ultrasonography/MRI fusion biopsies. Monoexponential 2-point and multipoint fits of standard diffusion and of UHB diffusion were calculated with incremental b-values. Furthermore, a kurtosis fit with parameters Dapp and Kapp with incremental b-values was obtained. Each parameter was examined for prediction of clinically significant prostate cancer using bootstrapped receiver operating characteristics and decision curve analysis. Parameter models were compared using Vuong test. - Results - Fifty of 73 men (age, 66 years [interquartile range, 61-72]; prostate-specific antigen, 6.6 ng/mL [interquartile range, 5-9.7]) had 64 MRI-detected lesions. The performance of SD-ADC-2b-1000 (area under the curve, 0.82) and SD-ADC-2b-1500 (area under the curve, 0.82) was not statistically different (P = 0.99), with SD-ADC-2b-1500 selected as reference. Compared with the reference model, none of the 19 tested logistic regression parameter models including multipoint and 2-point UHB-ADC, Dapp, and Kapp with incremental b-values of up to 4000 s/mm2 outperformed SD-ADC-2b-1500 (all P's > 0.05). Decision curve analysis confirmed these results indicating no higher net benefit for UHB parameters in comparison to SD-ADC-2b-1500 in the clinically important range from 3% to 20% of cancer threshold probability. Net reduction analysis showed no reduction of MR lesions requiring biopsy. - Conclusions - Despite evaluation of a large b-value range and inclusion of 2-point, multipoint, and kurtosis models, none of the parameters provided better predictive performance than standard 2-point ADC measurements using b-values 50/1000 or 50/1500. Our results suggest that most of the diagnostic benefits available in diffusion MRI are already represented in an ADC composed of one low and one 1000 to 1500 s/mm2 b-value. | ||
| 700 | 1 | |a Kuder, Tristan Anselm |e VerfasserIn |0 (DE-588)14203911X |0 (DE-627)704126338 |0 (DE-576)326749675 |4 aut | |
| 700 | 1 | |a Tichy, Diana |e VerfasserIn |0 (DE-588)1028040873 |0 (DE-627)730210081 |0 (DE-576)375518258 |4 aut | |
| 700 | 1 | |a Radtke, Jan Philipp |d 1985- |e VerfasserIn |0 (DE-588)1020328290 |0 (DE-627)688118089 |0 (DE-576)360178170 |4 aut | |
| 700 | 1 | |a Görtz, Magdalena |d 1992- |e VerfasserIn |0 (DE-588)1166813657 |0 (DE-627)1030681392 |0 (DE-576)510916600 |4 aut | |
| 700 | 1 | |a Schütz, Viktoria |e VerfasserIn |0 (DE-588)1183860021 |0 (DE-627)1663385335 |4 aut | |
| 700 | 1 | |a Stenzinger, Albrecht |e VerfasserIn |0 (DE-588)139606106 |0 (DE-627)703395238 |0 (DE-576)312432755 |4 aut | |
| 700 | 1 | |a Hohenfellner, Markus |d 1958- |e VerfasserIn |0 (DE-588)133862518 |0 (DE-627)557857988 |0 (DE-576)300155263 |4 aut | |
| 700 | 1 | |a Schlemmer, Heinz-Peter |d 1961- |e VerfasserIn |0 (DE-588)1025559967 |0 (DE-627)722927142 |0 (DE-576)17334805X |4 aut | |
| 700 | 1 | |a Bonekamp, David |d 1977- |e VerfasserIn |0 (DE-588)128868104 |0 (DE-627)383668581 |0 (DE-576)297371797 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Investigative radiology |d Philadelphia, Pa. : Lippincott Williams & Wilkins, 1966 |g 56(2021), 2, Seite 94-102 |h Online-Ressource |w (DE-627)326645322 |w (DE-600)2041543-6 |w (DE-576)09442568X |x 1536-0210 |7 nnas |a Measured multipoint ultra-high b-value diffusion MRI in the assessment of MRI-detected prostate lesions |
| 773 | 1 | 8 | |g volume:56 |g year:2021 |g number:2 |g pages:94-102 |g extent:9 |a Measured multipoint ultra-high b-value diffusion MRI in the assessment of MRI-detected prostate lesions |
| 856 | 4 | 0 | |u https://doi.org/10.1097/RLI.0000000000000712 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://journals.lww.com/investigativeradiology/Abstract/2021/02000/Measured_Multipoint_Ultra_High_b_Value_Diffusion.4.aspx |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20210311 | ||
| 993 | |a Article | ||
| 994 | |a 2021 | ||
| 998 | |g 128868104 |a Bonekamp, David |m 128868104:Bonekamp, David |d 50000 |e 50000PB128868104 |k 0/50000/ |p 10 |y j | ||
| 998 | |g 1025559967 |a Schlemmer, Heinz-Peter |m 1025559967:Schlemmer, Heinz-Peter |d 50000 |e 50000PS1025559967 |k 0/50000/ |p 9 | ||
| 998 | |g 133862518 |a Hohenfellner, Markus |m 133862518:Hohenfellner, Markus |d 910000 |d 910200 |e 910000PH133862518 |e 910200PH133862518 |k 0/910000/ |k 1/910000/910200/ |p 8 | ||
| 998 | |g 139606106 |a Stenzinger, Albrecht |m 139606106:Stenzinger, Albrecht |d 910000 |d 912000 |e 910000PS139606106 |e 912000PS139606106 |k 0/910000/ |k 1/910000/912000/ |p 7 | ||
| 998 | |g 1183860021 |a Schütz, Viktoria |m 1183860021:Schütz, Viktoria |d 910000 |d 910200 |e 910000PS1183860021 |e 910200PS1183860021 |k 0/910000/ |k 1/910000/910200/ |p 6 | ||
| 998 | |g 1166813657 |a Görtz, Magdalena |m 1166813657:Görtz, Magdalena |d 910000 |d 910200 |e 910000PG1166813657 |e 910200PG1166813657 |k 0/910000/ |k 1/910000/910200/ |p 5 | ||
| 998 | |g 1020328290 |a Radtke, Jan Philipp |m 1020328290:Radtke, Jan Philipp |d 50000 |e 50000PR1020328290 |k 0/50000/ |p 4 | ||
| 998 | |g 1028040873 |a Tichy, Diana |m 1028040873:Tichy, Diana |d 50000 |e 50000PT1028040873 |k 0/50000/ |p 3 | ||
| 998 | |g 14203911X |a Kuder, Tristan Anselm |m 14203911X:Kuder, Tristan Anselm |d 130000 |e 130000PK14203911X |k 0/130000/ |p 2 | ||
| 998 | |g 118568624X |a Tavakoli, Andrej |m 118568624X:Tavakoli, Andrej |d 50000 |e 50000PT118568624X |k 0/50000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1751086658 |e 3884704664 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1751086658","person":[{"role":"aut","family":"Tavakoli","display":"Tavakoli, Andrej","given":"Andrej"},{"display":"Kuder, Tristan Anselm","given":"Tristan Anselm","family":"Kuder","role":"aut"},{"display":"Tichy, Diana","given":"Diana","family":"Tichy","role":"aut"},{"given":"Jan Philipp","display":"Radtke, Jan Philipp","family":"Radtke","role":"aut"},{"given":"Magdalena","display":"Görtz, Magdalena","family":"Görtz","role":"aut"},{"given":"Viktoria","display":"Schütz, Viktoria","role":"aut","family":"Schütz"},{"role":"aut","family":"Stenzinger","given":"Albrecht","display":"Stenzinger, Albrecht"},{"given":"Markus","display":"Hohenfellner, Markus","role":"aut","family":"Hohenfellner"},{"family":"Schlemmer","role":"aut","given":"Heinz-Peter","display":"Schlemmer, Heinz-Peter"},{"family":"Bonekamp","role":"aut","given":"David","display":"Bonekamp, David"}],"note":["Gesehen am 01.12.2021"],"language":["eng"],"name":{"displayForm":["Tavakoli, Anoshirwan Andrej MD; Kuder, Tristan Anselm PhD; Tichy, Diana PhD; Radtke, Jan Philipp MD; Görtz, Magdalena MD; Schütz, Viktoria MD; Stenzinger, Albrecht MD; Hohenfellner, Markus MD; Schlemmer, Heinz-Peter MD, PhD; Bonekamp, David MD"]},"relHost":[{"part":{"year":"2021","volume":"56","issue":"2","pages":"94-102","extent":"9","text":"56(2021), 2, Seite 94-102"},"language":["eng"],"pubHistory":["1.1966 -"],"note":["Gesehen am 01.03.11"],"disp":"Measured multipoint ultra-high b-value diffusion MRI in the assessment of MRI-detected prostate lesionsInvestigative radiology","type":{"media":"Online-Ressource","bibl":"periodical"},"recId":"326645322","physDesc":[{"extent":"Online-Ressource"}],"id":{"issn":["1536-0210"],"eki":["326645322"],"zdb":["2041543-6"]},"title":[{"title_sort":"Investigative radiology","subtitle":"a journal of clinical and laboratory research","title":"Investigative radiology"}],"origin":[{"publisher":"Lippincott Williams & Wilkins ; Ovid","dateIssuedDisp":"1966-","dateIssuedKey":"1966","publisherPlace":"Philadelphia, Pa. ; [Erscheinungsort nicht ermittelbar]"}]}],"origin":[{"dateIssuedDisp":"February 2021","dateIssuedKey":"2021"}],"title":[{"title_sort":"Measured multipoint ultra-high b-value diffusion MRI in the assessment of MRI-detected prostate lesions","title":"Measured multipoint ultra-high b-value diffusion MRI in the assessment of MRI-detected prostate lesions"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"id":{"eki":["1751086658"],"doi":["10.1097/RLI.0000000000000712"]},"physDesc":[{"extent":"9 S."}]} | ||
| SRT | |a TAVAKOLIANMEASUREDMU2021 | ||