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Cellular uptake and localization of inhaled gold nanoparticles in lungs of mice with chronic obstructive pulmonary disease

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Inhalative nanocarriers for local or systemic therapy are promising. Gold nanoparticles (AuNP) have been widely considered as candidate material. Knowledge about their interaction with the lungs is required, foremost their uptake by surface macrophages and epithelial cells.

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Main Authors: Geiser, Marianne (Author) , Quaile, Oliver (Author) , Wenk, Alexander (Author) , Wigge, Christoph (Author) , Eigeldinger-Berthou, Sylvie (Author) , Hirn, Stephanie (Author) , Schäffler, Martin (Author) , Schleh, Carsten (Author) , Möller, Winfried (Author) , Mall, Marcus A. (Author) , Kreyling, Wolfgang G. (Author)
Format: Article (Journal)
Language:English
Published: 16 May 2013
In: Particle and fibre toxicology
Year: 2013, Volume: 10, Pages: 1-10
ISSN:1743-8977
DOI:10.1186/1743-8977-10-19
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1743-8977-10-19
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Author Notes:Marianne Geiser, Oliver Quaile, Alexander Wenk, Christoph Wigge, Sylvie Eigeldinger-Berthou, Stephanie Hirn, Martin Schäffler, Carsten Schleh, Winfried Möller, Marcus A Mall and Wolfgang G Kreyling

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