Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells

Ganglioglioma is a rare CNS tumor with a benign biological behavior. Recently, the BRAF V600E mutation was identified in approximately 20 % of gangliogliomas. Here, we analyzed a total of 71 gangliogliomas for BRAF V600E mutational status by VE1 immunohistochemistry and direct DNA sequencing. The BR...

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Main Authors: Kölsche, Christian (Author) , Wöhrer, Adelheid (Author) , Jeibmann, Astrid (Author) , Schittenhelm, Jens (Author) , Schindler, Genevieve (Author) , Preusser, Matthias (Author) , Lasitschka, Felix (Author) , Deimling, Andreas von (Author) , Capper, David (Author)
Format: Article (Journal)
Language:English
Published: 24 February 2013
In: Acta neuropathologica
Year: 2013, Volume: 125, Issue: 6, Pages: 891-900
ISSN:1432-0533
DOI:10.1007/s00401-013-1100-2
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00401-013-1100-2
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Author Notes:Christian Koelsche, Adelheid Wöhrer, Astrid Jeibmann, Jens Schittenhelm, Genevieve Schindler, Matthias Preusser, Felix Lasitschka, Andreas von Deimling, David Capper
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BRAF V600E mutations in nevi and melanocytic tumors of uncertain malignant potential by Seitz-Alghrouz, Ruth Christin (Author) , Deimling, Andreas von (Author) ,


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