Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells
Ganglioglioma is a rare CNS tumor with a benign biological behavior. Recently, the BRAF V600E mutation was identified in approximately 20 % of gangliogliomas. Here, we analyzed a total of 71 gangliogliomas for BRAF V600E mutational status by VE1 immunohistochemistry and direct DNA sequencing. The BR...
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| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
24 February 2013
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| In: |
Acta neuropathologica
Year: 2013, Volume: 125, Issue: 6, Pages: 891-900 |
| ISSN: | 1432-0533 |
| DOI: | 10.1007/s00401-013-1100-2 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00401-013-1100-2 |
| Author Notes: | Christian Koelsche, Adelheid Wöhrer, Astrid Jeibmann, Jens Schittenhelm, Genevieve Schindler, Matthias Preusser, Felix Lasitschka, Andreas von Deimling, David Capper |
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