Mechanisms of disease: pathophysiological concepts of stroke in hemodynamic risk zones : do hypoperfusion and embolism interact?

Over the past century, the pathophysiology of ischemia in the borderzones between the large cerebral arteries has been the topic of considerable debate. Two seemingly mutually exclusive mechanisms—hemodynamic failure and microembolism—have been proposed to explain this phenomenon. As Förster et al....

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Hauptverfasser: Förster, Alex (VerfasserIn) , Szabo, Kristina (VerfasserIn) , Hennerici, Michael G. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 26 February 2008
In: Nature Clinical Practice. Neurology
Year: 2008, Jahrgang: 4, Heft: 4, Pages: 216-225
ISSN:1745-8358
DOI:10.1038/ncpneuro0752
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/ncpneuro0752
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/ncpneuro0752
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Verfasserangaben:Alex Förster, Kristina Szabo, and Michael G. Hennerici
Beschreibung
Zusammenfassung:Over the past century, the pathophysiology of ischemia in the borderzones between the large cerebral arteries has been the topic of considerable debate. Two seemingly mutually exclusive mechanisms—hemodynamic failure and microembolism—have been proposed to explain this phenomenon. As Förster et al. discuss in this article, a new model of borderzone infarction, incorporating both hypoperfusion and microembolism, is now emerging.
Beschreibung:Gesehen am 24.03.2021
Beschreibung:Online Resource
ISSN:1745-8358
DOI:10.1038/ncpneuro0752