Buchumschlag

Synthesis of peptide radiopharmaceuticals for the therapy and diagnosis of tumor diseases

Despite the advances in molecular biology and biochemistry, the prognosis of patients suffering from tumor diseases remains poor. The limited therapeutic success can be explained by the insufficient performance of the common chemotherapeutic drugs that lack the ability to specifically target tumor t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Jamous, Mazen (VerfasserIn) , Haberkorn, Uwe (VerfasserIn) , Mier, Walter (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 14 March 2013
In: Molecules
Year: 2013, Jahrgang: 18, Heft: 3, Pages: 3379-3409
ISSN:1420-3049
DOI:10.3390/molecules18033379
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/molecules18033379
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/1420-3049/18/3/3379
Volltext
Verfasserangaben:Mazen Jamous, Uwe Haberkorn and Walter Mier

MARC

LEADER 00000caa a2200000 c 4500
001 1752366778
003 DE-627
005 20230427020449.0
007 cr uuu---uuuuu
008 210324s2013 xx |||||o 00| ||eng c
024 7 |a 10.3390/molecules18033379  |2 doi 
035 |a (DE-627)1752366778 
035 |a (DE-599)KXP1752366778 
035 |a (OCoLC)1341400978 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Jamous, Mazen  |e VerfasserIn  |0 (DE-588)1119480590  |0 (DE-627)872791203  |0 (DE-576)479925380  |4 aut 
245 1 0 |a Synthesis of peptide radiopharmaceuticals for the therapy and diagnosis of tumor diseases  |c Mazen Jamous, Uwe Haberkorn and Walter Mier 
264 1 |c 14 March 2013 
300 |a 31 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 24.03.2021 
520 |a Despite the advances in molecular biology and biochemistry, the prognosis of patients suffering from tumor diseases remains poor. The limited therapeutic success can be explained by the insufficient performance of the common chemotherapeutic drugs that lack the ability to specifically target tumor tissues. Recently peptide radiopharmaceuticals have been developed that enable the concurrent imaging and therapy of tumors expressing a specific target. Here, with a special emphasis on the synthesis of the building blocks required for the complexation of metallic radioisotopes, the requirements to the design and synthesis of radiolabeled peptides for clinical applications are described. 
650 4 |a carrier molecules 
650 4 |a chelator 
650 4 |a diagnostic imaging 
650 4 |a medicinal application 
650 4 |a peptides 
650 4 |a prosthetic groups 
650 4 |a radionuclides 
650 4 |a radiopharmaceutical 
650 4 |a radiotherapeutics 
700 1 |a Haberkorn, Uwe  |d 1959-  |e VerfasserIn  |0 (DE-588)1022913905  |0 (DE-627)717331245  |0 (DE-576)366166352  |4 aut 
700 1 |a Mier, Walter  |d 1966-  |e VerfasserIn  |0 (DE-588)12029026X  |0 (DE-627)69653567X  |0 (DE-576)292141599  |4 aut 
773 0 8 |i Enthalten in  |t Molecules  |d Basel : MDPI, 1996  |g 18(2013), 3, Seite 3379-3409  |h Online-Ressource  |w (DE-627)311313132  |w (DE-600)2008644-1  |w (DE-576)281192456  |x 1420-3049  |7 nnas  |a Synthesis of peptide radiopharmaceuticals for the therapy and diagnosis of tumor diseases 
773 1 8 |g volume:18  |g year:2013  |g number:3  |g pages:3379-3409  |g extent:31  |a Synthesis of peptide radiopharmaceuticals for the therapy and diagnosis of tumor diseases 
856 4 0 |u https://doi.org/10.3390/molecules18033379  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://www.mdpi.com/1420-3049/18/3/3379  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20210324 
993 |a Article 
994 |a 2013 
998 |g 12029026X  |a Mier, Walter  |m 12029026X:Mier, Walter  |d 910000  |d 911400  |e 910000PM12029026X  |e 911400PM12029026X  |k 0/910000/  |k 1/910000/911400/  |p 3  |y j 
998 |g 1022913905  |a Haberkorn, Uwe  |m 1022913905:Haberkorn, Uwe  |d 910000  |d 911400  |e 910000PH1022913905  |e 911400PH1022913905  |k 0/910000/  |k 1/910000/911400/  |p 2 
998 |g 1119480590  |a Jamous, Mazen  |m 1119480590:Jamous, Mazen  |d 700000  |d 710000  |e 700000PJ1119480590  |e 710000PJ1119480590  |k 0/700000/  |k 1/700000/710000/  |p 1  |x j 
999 |a KXP-PPN1752366778  |e 3893723439 
BIB |a Y 
SER |a journal 
JSO |a {"origin":[{"dateIssuedKey":"2013","dateIssuedDisp":"14 March 2013"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"person":[{"role":"aut","display":"Jamous, Mazen","given":"Mazen","family":"Jamous"},{"role":"aut","display":"Haberkorn, Uwe","given":"Uwe","family":"Haberkorn"},{"given":"Walter","family":"Mier","display":"Mier, Walter","role":"aut"}],"title":[{"title":"Synthesis of peptide radiopharmaceuticals for the therapy and diagnosis of tumor diseases","title_sort":"Synthesis of peptide radiopharmaceuticals for the therapy and diagnosis of tumor diseases"}],"note":["Gesehen am 24.03.2021"],"relHost":[{"language":["eng"],"part":{"pages":"3379-3409","volume":"18","extent":"31","issue":"3","year":"2013","text":"18(2013), 3, Seite 3379-3409"},"disp":"Synthesis of peptide radiopharmaceuticals for the therapy and diagnosis of tumor diseasesMolecules","physDesc":[{"extent":"Online-Ressource"}],"name":{"displayForm":["Molecular Diversity Preservation International"]},"id":{"eki":["311313132"],"issn":["1420-3049"],"zdb":["2008644-1"]},"recId":"311313132","note":["Gesehen am 25.06.20"],"type":{"media":"Online-Ressource","bibl":"periodical"},"origin":[{"dateIssuedKey":"1996","publisherPlace":"Basel","dateIssuedDisp":"1996-","publisher":"MDPI"}],"pubHistory":["1.1996 -"],"title":[{"title":"Molecules","subtitle":"a journal of synthetic chemistry and natural product chemistry","title_sort":"Molecules"}]}],"name":{"displayForm":["Mazen Jamous, Uwe Haberkorn and Walter Mier"]},"recId":"1752366778","id":{"eki":["1752366778"],"doi":["10.3390/molecules18033379"]},"language":["eng"],"physDesc":[{"extent":"31 S."}]} 
SRT |a JAMOUSMAZESYNTHESISO1420 

Ähnliche Einträge