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Marginal donors: can older donor hearts tolerate prolonged cold ischemic storage?

Both advanced donor age and prolonged ischemic time are significant risk factors for the 1-year mortality. However, its functional consequences have not been fully evaluated in the early-phase after transplantation; even early graft dysfunction is the main determinant of long-term outcome following...

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Main Authors: Korkmaz-İçöz, Sevil (Author) , Bährle-Szabó, Susanne (Author) , Loganathan, Sivakkanan (Author) , Li, Shiliang (Author) , Karck, Matthias (Author) , Szabó, Gábor (Author)
Format: Article (Journal)
Language:English
Published: 15 August 2013
In: Aging clinical and experimental research
Year: 2013, Volume: 25, Issue: 5, Pages: 597-600
ISSN:1720-8319
DOI:10.1007/s40520-013-0131-9
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s40520-013-0131-9
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Author Notes:Sevil Korkmaz, Susanne Bährle-Szabó, Sivakkanan Loganathan, Shiliang Li, Matthias Karck, Gábor Szabó
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Summary:Both advanced donor age and prolonged ischemic time are significant risk factors for the 1-year mortality. However, its functional consequences have not been fully evaluated in the early-phase after transplantation; even early graft dysfunction is the main determinant of long-term outcome following transplantation. We evaluated in vivo left-ventricular (LV) cardiac and coronary vascular function of old-donor grafts after short and prolonged cold ischemic times in rats 1 h after heart transplantation.
Item Description:Gesehen am 18.11.2021
Physical Description:Online Resource
ISSN:1720-8319
DOI:10.1007/s40520-013-0131-9

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