Marginal donors: can older donor hearts tolerate prolonged cold ischemic storage?
Both advanced donor age and prolonged ischemic time are significant risk factors for the 1-year mortality. However, its functional consequences have not been fully evaluated in the early-phase after transplantation; even early graft dysfunction is the main determinant of long-term outcome following...
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| Main Authors: | , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
15 August 2013
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| In: |
Aging clinical and experimental research
Year: 2013, Volume: 25, Issue: 5, Pages: 597-600 |
| ISSN: | 1720-8319 |
| DOI: | 10.1007/s40520-013-0131-9 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s40520-013-0131-9 |
| Author Notes: | Sevil Korkmaz, Susanne Bährle-Szabó, Sivakkanan Loganathan, Shiliang Li, Matthias Karck, Gábor Szabó |
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| 520 | |a Both advanced donor age and prolonged ischemic time are significant risk factors for the 1-year mortality. However, its functional consequences have not been fully evaluated in the early-phase after transplantation; even early graft dysfunction is the main determinant of long-term outcome following transplantation. We evaluated in vivo left-ventricular (LV) cardiac and coronary vascular function of old-donor grafts after short and prolonged cold ischemic times in rats 1 h after heart transplantation. | ||
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