Severe forward flexion of the trunk in Parkinson's disease: focal myopathy of the paraspinal muscles mimicking camptocormia
Pronounced forward flexion of the trunk, often termed camptocormia, is a typical symptom of patients with Parkinson's disease. In 4 parkinsonian patients with camptocormia, paraspinal muscles were studied by electromyography (EMG) and axial computerized tomography (CT) or magnetic resonance ima...
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| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
24 January 2003
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| In: |
Movement disorders
Year: 2003, Jahrgang: 18, Heft: 4, Pages: 408-414 |
| ISSN: | 1531-8257 |
| DOI: | 10.1002/mds.10385 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/mds.10385 Verlag, lizenzpflichtig, Volltext: https://movementdisorders.onlinelibrary.wiley.com/doi/abs/10.1002/mds.10385 
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| Verfasserangaben: | Wolf-Rüdiger Schäbitz, Katharina Glatz, Christian Schuhan, Clemens Sommer, Christian Berger, Markus Schwaninger, Marius Hartmann, Hans Hilmar Goebel, and Hans-Michael Meinck |
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| 520 | |a Pronounced forward flexion of the trunk, often termed camptocormia, is a typical symptom of patients with Parkinson's disease. In 4 parkinsonian patients with camptocormia, paraspinal muscles were studied by electromyography (EMG) and axial computerized tomography (CT) or magnetic resonance imaging (MRI) scans and muscle biopsy. EMG of the lumbar and thoracic paravertebral muscles showed abundant fibrillations, positive sharp waves, and bizarre high-frequency discharges. Spinal CT and MRI scans revealed variable degrees of atrophy and fatty replacement of the thoracolumbar paraspinal muscles on both sides. No other signs of neuromuscular disease were found. Biopsy of the paraspinal muscles revealed end-stage myopathy with autophagic vacuoles, chronic inflammatory myopathy, unspecific myopathic changes, or mitochondrial myopathy. In parkinsonian patients with pronounced forward flexion of the trunk, myopathy confined to the erector spinae muscles must be considered. © 2003 Movement Disorder Society | ||
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