rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Specificity of anti-human CD95 (APO-1/Fas) antibodies
  name:
    name part: Schmitz, Ingo
    name part: 1971-
    role:
      role term: creator
    role:
      role term: VerfasserIn
    role:
      role term: aut
  name:
    name part: Krammer, Peter H.
    name part: 1946-
    role:
      role term: VerfasserIn
    role:
      role term: aut
  type of resource: text
  origin info:
    place:
      place term: xx
    date issued: 2002
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 4
  abstract: The CD95 (APO-1/Fas) death receptor plays an important role in many physiological and pathophysiological systems. Thus, the CD95 system contributes to activation-induced cell death. Therefore, reliable antibodies recognizing human CD95 are of great interest. Detection of CD95 expression often relies on antibodies, e.g., suitable for Western blotting. To detect CD95, we compared the specificity of nine different anti-human CD95 antibodies recognizing different epitopes by using postnuclear supernatants of four different cell lines. Only two of the antibodies tested, both directed against intracellular epitopes of human CD95, detected endogenous human CD95 by Western blotting. Therefore, we conclude that results obtained with other anti-CD95 antibodies should be treated with caution.
  note: Ingo Schmitz, Andreas Krueger, Sven Baumann, Sabine Kirchhoff, and Peter H Krammer
  note: Gesehen am 14.04.2021
  subject:
    topic: Antibodies
  subject:
    topic: Apoptosis
  subject:
    topic: CD95/APO-1/Fas
  subject:
    topic: Western blot
  classification: 33
  related item:
    title info:
      title: Biochemical and biophysical research communications
    name:
      name part: Specificity of anti-human CD95 (APO-1/Fas) antibodies
    origin info:
      publisher: [Amsterdam] : Elsevier B.V., 1959
    physical description:
      extent: Online-Ressource
    identifier: 1090-2104
    identifier: (DE-627)254231691
    identifier: (DE-600)1461396-7
    identifier: (DE-576)103373039
    part:
      text: 297(2002), 3, Seite 459-462
  related item:
    name:
      name part: Specificity of anti-human CD95 (APO-1/Fas) antibodies
    part:
      text: volume:297
    part:
      text: year:2002
    part:
      text: number:3
    part:
      text: pages:459-462
    part:
      text: extent:4
  identifier: https://doi.org/10.1016/S0006-291X(02)02242-8
  identifier: https://www.sciencedirect.com/science/article/pii/S0006291X02022428
  record info:
    record content source: DE-627
    record creation date: 210414
    record change date: 20220819164243.0
    record identifier: 1754868169
    language of cataloging:
      language term: ger