Low risk of the TMPRSS2 inhibitor camostat mesylate and its metabolite GBPA to act as perpetrators of drug-drug interactions
Camostat mesylate, a potent inhibitor of the human transmembrane protease, serine 2 (TMPRSS2), is currently under investigation for its effectiveness in COVID-19 patients. For its safe application, the risks of camostat mesylate to induce pharmacokinetic drug-drug interactions with co-administered d...
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| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
27 February 2021
|
| In: |
Chemico-biological interactions
Year: 2021, Volume: 338, Pages: 1-7 |
| ISSN: | 1872-7786 |
| DOI: | 10.1016/j.cbi.2021.109428 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.cbi.2021.109428 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0009279721000648 |
| Author Notes: | Johanna Weiss, Gzona Bajraktari-Sylejmani, Walter Emil Haefeli |