Adding cetuximab to paclitaxel and carboplatin for first-line treatment of carcinoma of unknown primary (CUP): results of the Phase 2 AIO trial PACET-CUP
Patients with carcinoma of unknown primary (CUP) have a dismal prognosis, even when treated with multi-agent chemotherapy. We hypothesised that adding the epidermal growth-factor receptor (EGFR) inhibitor cetuximab to standard first-line chemotherapy with paclitaxel and carboplatin would improve PFS...
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| Hauptverfasser: | , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2021
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| In: |
British journal of cancer
Year: 2021, Jahrgang: 124, Heft: 4, Pages: 721-727 |
| ISSN: | 1532-1827 |
| DOI: | 10.1038/s41416-020-01141-8 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41416-020-01141-8 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41416-020-01141-8 
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| Verfasserangaben: | Gunnar Folprecht, Karolin Trautmann, Alexander Stein, Gerdt Huebner, Michael Stahl, Stefan Kasper, Albrecht Kretzschmar, Claus-Henning Köhne, Viktor Grünwald, Ralf-Dieter Hofheinz, Katharina Schütte, Harald Löffler, Carsten Bokemeyer, Alwin Krämer and Arbeitsgemeinschaft Internistische Onkologie (AIO) - CUP Group |
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| 520 | |a Patients with carcinoma of unknown primary (CUP) have a dismal prognosis, even when treated with multi-agent chemotherapy. We hypothesised that adding the epidermal growth-factor receptor (EGFR) inhibitor cetuximab to standard first-line chemotherapy with paclitaxel and carboplatin would improve PFS and RR in unfavourable CUP. | ||
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