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PI3K/AKT signaling is essential for communication between tissue-infiltrating mast cells, macrophages, and epithelial cells in colitis-induced cancer

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Purpose: To understand signaling pathways that shape inflamed tissue and predispose to cancer is critical for effective prevention and therapy for chronic inflammatory diseases. We have explored phosphoinositide 3-kinase (PI3K) activity in human inflammatory bowel diseases and mouse colitis models....

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Main Authors: Khan, Mohammad Wasim Kayyum (Author) , Keshavarzian, Ali (Author) , Gounaris, Elias (Author) , Melson, Joshua E. (Author) , Cheon, Eric C. (Author) , Blatner, Nichole R. (Author) , Chen, Zongmin E. (Author) , Tsai, Fu-Nien (Author) , Lee, Goo (Author) , Ryu, Hyunji (Author) , Barrett, Terrence A. (Author) , Bentrem, David J. (Author) , Beckhove, Philipp (Author) , Khazaie, Khashayarsha (Author)
Format: Article (Journal)
Language:English
Published: March 13, 2013
In: Clinical cancer research
Year: 2013, Volume: 19, Issue: 9, Pages: 2342-2354
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-12-2623
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1158/1078-0432.CCR-12-2623
Verlag, lizenzpflichtig, Volltext: https://clincancerres.aacrjournals.org/content/19/9/2342
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Author Notes:Mohammad W. Khan, Ali Keshavarzian, Elias Gounaris, Joshua E. Melson, Eric C. Cheon, Nichole R. Blatner, Zongmin E. Chen, Fu-Nien Tsai, Goo Lee, Hyunji Ryu, Terrence A. Barrett, David J. Bentrem, Philipp Beckhove, and Khashayarsha Khazaie
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PI3K/AKT signaling is essential for communication between tissue infiltrating mast cells, macrophages, and epithelial cells in colitis-induced cancer by Khan, Mohammad Wasim Kayyum (Author)

2013

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