The proteome of human brain microdialysate
Cerebral microdialysis has been established as a monitoring tool in neurocritically ill patients suffering from severe stroke. The technique allows to sample small molecules in the brain tissue for subsequent biochemical analysis. In this study, we investigated the proteomic profile of human cerebra...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
14 December 2003
|
| In: |
Proteome science
Year: 2003, Jahrgang: 1, Pages: 1-9 |
| ISSN: | 1477-5956 |
| DOI: | 10.1186/1477-5956-1-7 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1477-5956-1-7
|
| Verfasserangaben: | Martin H. Maurer, Christian Berger, Margit Wolf, Carsten D. Fütterer, Robert E. Feldmann, Stefan Schwab and Wolfgang Kuschinsky |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 175713011X | ||
| 003 | DE-627 | ||
| 005 | 20230426114250.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 210505s2003 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1186/1477-5956-1-7 |2 doi | |
| 035 | |a (DE-627)175713011X | ||
| 035 | |a (DE-599)KXP175713011X | ||
| 035 | |a (OCoLC)1341408170 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Maurer, Martin H. |d 1971- |e VerfasserIn |0 (DE-588)121878112 |0 (DE-627)081593309 |0 (DE-576)182104672 |4 aut | |
| 245 | 1 | 4 | |a The proteome of human brain microdialysate |c Martin H. Maurer, Christian Berger, Margit Wolf, Carsten D. Fütterer, Robert E. Feldmann, Stefan Schwab and Wolfgang Kuschinsky |
| 264 | 1 | |c 14 December 2003 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 05.05.2021 | ||
| 520 | |a Cerebral microdialysis has been established as a monitoring tool in neurocritically ill patients suffering from severe stroke. The technique allows to sample small molecules in the brain tissue for subsequent biochemical analysis. In this study, we investigated the proteomic profile of human cerebral microdialysate and if the identified proteins might be useful predictors for disease characteristics in stroke for tissue at risk in the contralateral hemisphere. We analysed cerebral protein expression in microdialysate from three stroke patients sampled from the hemisphere contralateral to the lesion. Using a proteomic approach based on two-dimensional gel electrophoresis and subsequent mass spectrometry, we created a protein map for the global protein expression pattern of human microdialyste. | ||
| 650 | 4 | |a Brain Edema | |
| 650 | 4 | |a Contralateral Hemisphere | |
| 650 | 4 | |a Microdialysis Probe | |
| 650 | 4 | |a Protein Spot | |
| 650 | 4 | |a Stroke Patient | |
| 700 | 1 | |a Berger, Christian |e VerfasserIn |0 (DE-588)1067266089 |0 (DE-627)818567538 |0 (DE-576)426526279 |4 aut | |
| 700 | 1 | |a Wolf, Margit |e VerfasserIn |4 aut | |
| 700 | 1 | |a Fütterer, Carsten Dietmar |d 1972- |e VerfasserIn |0 (DE-588)124640249 |0 (DE-627)575608560 |0 (DE-576)294425357 |4 aut | |
| 700 | 1 | |a Feldmann, Robert Enrico |d 1970- |e VerfasserIn |0 (DE-588)129555991 |0 (DE-627)47271578X |0 (DE-576)297720554 |4 aut | |
| 700 | 1 | |a Schwab, Stefan |d 1961- |e VerfasserIn |0 (DE-588)13251463X |0 (DE-627)523328427 |0 (DE-576)299194973 |4 aut | |
| 700 | 1 | |a Kuschinsky, Wolfgang |d 1944- |e VerfasserIn |0 (DE-588)1145453708 |0 (DE-627)1005597847 |0 (DE-576)161874711 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Proteome science |d London : BioMed Central, 2003 |g 1(2003), Artikel-ID 7, Seite 1-9 |h Online-Ressource |w (DE-627)383961440 |w (DE-600)2141087-2 |w (DE-576)110738454 |x 1477-5956 |7 nnas |a The proteome of human brain microdialysate |
| 773 | 1 | 8 | |g volume:1 |g year:2003 |g elocationid:7 |g pages:1-9 |g extent:9 |a The proteome of human brain microdialysate |
| 856 | 4 | 0 | |u https://doi.org/10.1186/1477-5956-1-7 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20210505 | ||
| 993 | |a Article | ||
| 994 | |a 2003 | ||
| 998 | |g 1145453708 |a Kuschinsky, Wolfgang |m 1145453708:Kuschinsky, Wolfgang |d 50000 |d 53200 |e 50000PK1145453708 |e 53200PK1145453708 |k 0/50000/ |k 1/50000/53200/ |p 7 |y j | ||
| 998 | |g 13251463X |a Schwab, Stefan |m 13251463X:Schwab, Stefan |d 910000 |d 911100 |e 910000PS13251463X |e 911100PS13251463X |k 0/910000/ |k 1/910000/911100/ |p 6 | ||
| 998 | |g 129555991 |a Feldmann, Robert Enrico |m 129555991:Feldmann, Robert Enrico |d 50000 |e 50000PF129555991 |k 0/50000/ |p 5 | ||
| 998 | |g 124640249 |a Fütterer, Carsten Dietmar |m 124640249:Fütterer, Carsten Dietmar |d 60000 |d 61600 |e 60000PF124640249 |e 61600PF124640249 |k 0/60000/ |k 1/60000/61600/ |p 4 | ||
| 998 | |g 1067266089 |a Berger, Christian |m 1067266089:Berger, Christian |d 50000 |e 50000PB1067266089 |k 0/50000/ |p 2 | ||
| 998 | |g 121878112 |a Maurer, Martin H. |m 121878112:Maurer, Martin H. |d 50000 |d 53200 |e 50000PM121878112 |e 53200PM121878112 |k 0/50000/ |k 1/50000/53200/ |p 1 |x j | ||
| 999 | |a KXP-PPN175713011X |e 3923317875 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"given":"Martin H.","role":"aut","display":"Maurer, Martin H.","family":"Maurer"},{"role":"aut","given":"Christian","family":"Berger","display":"Berger, Christian"},{"family":"Wolf","display":"Wolf, Margit","role":"aut","given":"Margit"},{"role":"aut","given":"Carsten Dietmar","family":"Fütterer","display":"Fütterer, Carsten Dietmar"},{"family":"Feldmann","display":"Feldmann, Robert Enrico","role":"aut","given":"Robert Enrico"},{"role":"aut","given":"Stefan","family":"Schwab","display":"Schwab, Stefan"},{"role":"aut","given":"Wolfgang","family":"Kuschinsky","display":"Kuschinsky, Wolfgang"}],"relHost":[{"pubHistory":["1.2003 -"],"id":{"zdb":["2141087-2"],"issn":["1477-5956"],"eki":["383961440"]},"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title_sort":"Proteome science","title":"Proteome science","subtitle":"PS"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"part":{"text":"1(2003), Artikel-ID 7, Seite 1-9","volume":"1","year":"2003","extent":"9","pages":"1-9"},"recId":"383961440","note":["Gesehen am 04.09.10"],"language":["eng"],"origin":[{"publisherPlace":"London","dateIssuedDisp":"2003-","publisher":"BioMed Central","dateIssuedKey":"2003"}],"disp":"The proteome of human brain microdialysateProteome science"}],"title":[{"title":"The proteome of human brain microdialysate","title_sort":"proteome of human brain microdialysate"}],"physDesc":[{"extent":"9 S."}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"id":{"doi":["10.1186/1477-5956-1-7"],"eki":["175713011X"]},"origin":[{"dateIssuedKey":"2003","dateIssuedDisp":"14 December 2003"}],"recId":"175713011X","language":["eng"],"note":["Gesehen am 05.05.2021"],"name":{"displayForm":["Martin H. Maurer, Christian Berger, Margit Wolf, Carsten D. Fütterer, Robert E. Feldmann, Stefan Schwab and Wolfgang Kuschinsky"]}} | ||
| SRT | |a MAURERMARTPROTEOMEOF1420 | ||