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Genetics of pulmonary hypertension and high-altitude pulmonary edema

Heritable pulmonary arterial hypertension (PAH) is an autosomal dominantly inherited disease caused by mutations in the bone morphogenetic protein receptor 2 (BMPR2) gene and/or genes of its signaling pathway in ~85% of patients. A genetic predisposition to high-altitude pulmonary edema (HAPE) has l...

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Main Authors: Eichstaedt, Christina (Author) , Benjamin, Nicola (Author) , Grünig, Ekkehard (Author)
Format: Article (Journal)
Language:English
Published: April 23, 2020
In: Journal of applied physiology
Year: 2020, Volume: 128, Issue: 5, Pages: 1432-1438
ISSN:1522-1601
DOI:10.1152/japplphysiol.00113.2020
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1152/japplphysiol.00113.2020
Verlag, lizenzpflichtig, Volltext: https://journals.physiology.org/doi/full/10.1152/japplphysiol.00113.2020
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Author Notes:Christina A. Eichstaedt, Nicola Benjamin, and Ekkehard Grünig

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