Phase 1 expansion cohort of ramucirumab plus pembrolizumab in advanced treatment-naive NSCLC

Introduction - Data of first-line ramucirumab plus pembrolizumab treatment of programmed death-ligand 1 (PD-L1)-positive NSCLC (cohort E) are reported (NCT02443324). - Methods - In this multicenter, open-label phase 1a/b trial, patients received ramucirumab 10 mg/kg and pembrolizumab 200 mg every 21...

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Main Authors: Herbst, Roy S. (Author) , Arkenau, Hendrik Tobias (Author) , Bendell, Johanna (Author) , Arrowsmith, Edward (Author) , Wermke, Martin (Author) , Soriano, Andres (Author) , Penel, Nicolas (Author) , Santana-Davila, Rafael (Author) , Bischoff, Helge (Author) , Chau, Ian (Author) , Mi, Gu (Author) , Wang, Hong (Author) , Rasmussen, Erik (Author) , Ferry, David (Author) , Chao, Bo H. (Author) , Paz-Ares, Luis (Author)
Format: Article (Journal)
Language:English
Published: 2021
In: Journal of thoracic oncology
Year: 2021, Volume: 16, Issue: 2, Pages: 289-298
ISSN:1556-1380
DOI:10.1016/j.jtho.2020.10.004
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jtho.2020.10.004
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1556086420308091
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Author Notes:Roy S. Herbst, MD, PhD, Hendrik Tobias Arkenau, MD, Johanna Bendell, MD, Edward Arrowsmith, MD, Martin Wermke, MD, Andres Soriano, MD, Nicolas Penel, MD, Rafael Santana-Davila, MD, Helge Bischoff, MD, Ian Chau, MD, Gu Mi, PhD, Hong Wang, PhD, Erik Rasmussen, PhD, David Ferry, MD, Bo H. Chao, MD, Luis Paz-Ares, MD
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Neoadjuvant anti-programmed death-1 immunotherapy by pembrolizumab in resectable non-small cell lung cancer: first clinical experience by Eichhorn, Florian (Author) , Klotz, Laura Valentina (Author) , Kriegsmann, Mark (Author) , Bischoff, Helge (Author) , Schneider, Marc (Author) , Muley, Thomas (Author) , Kriegsmann, Katharina (Author) , Haberkorn, Uwe (Author) , Heußel, Claus Peter (Author) , Savai, Rajkumar (Author) , Zörnig, Inka (Author) , Jäger, Dirk (Author) , Thomas, Michael (Author) , Hoffmann, Hans (Author) , Winter, Hauke (Author) , Eichhorn, Martin E. (Author) ,


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