Experiences with IL-1 blockade in systemic juvenile idiopathic arthritis: data from the German AID-registry
Systemic juvenile idiopathic arthritis (sJIA) is a complex disease with dysregulation of the innate immune system driven by cytokines. A major role is ascribed to interleukin-1β (IL-1β), supporting the autoinflammatory character of the disease and offering an effective blocking mechanism for treatme...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
22 March 2021
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| In: |
Pediatric rheumatology
Year: 2021, Jahrgang: 19, Pages: 1-12 |
| ISSN: | 1546-0096 |
| DOI: | 10.1186/s12969-021-00510-8 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12969-021-00510-8
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| Verfasserangaben: | Elke Lainka, Melanie Baehr, Bernadette Raszka, Johannes-Peter Haas, Boris Hügle, Nadine Fischer, Dirk Foell, Claas Hinze, Elisabeth Weissbarth-Riedel, Tilmann Kallinich, Gerd Horneff, Daniel Windschall, Eggert Lilienthal, Tim Niehues, Ulrich Neudorf, Rainer Berendes, Rolf-Michael Küster, Prasad Thomas Oommen, Christoph Rietschel, Thomas Lutz, Frank Weller-Heinemann, Klaus Tenbrock, Georg Leonhard Heubner, Jens Klotsche and Helmut Wittkowski |
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| 245 | 1 | 0 | |a Experiences with IL-1 blockade in systemic juvenile idiopathic arthritis |b data from the German AID-registry |c Elke Lainka, Melanie Baehr, Bernadette Raszka, Johannes-Peter Haas, Boris Hügle, Nadine Fischer, Dirk Foell, Claas Hinze, Elisabeth Weissbarth-Riedel, Tilmann Kallinich, Gerd Horneff, Daniel Windschall, Eggert Lilienthal, Tim Niehues, Ulrich Neudorf, Rainer Berendes, Rolf-Michael Küster, Prasad Thomas Oommen, Christoph Rietschel, Thomas Lutz, Frank Weller-Heinemann, Klaus Tenbrock, Georg Leonhard Heubner, Jens Klotsche and Helmut Wittkowski |
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| 520 | |a Systemic juvenile idiopathic arthritis (sJIA) is a complex disease with dysregulation of the innate immune system driven by cytokines. A major role is ascribed to interleukin-1β (IL-1β), supporting the autoinflammatory character of the disease and offering an effective blocking mechanism for treatment. Here we present clinical practice data from the German AID-registry for patients treated with IL-1 inhibition (IL-1i). | ||
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| 650 | 4 | |a Systemic juvenile idiopathic arthritis | |
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