3D-printed individualized tooth-borne tissue retraction devices compared to conventional dental splints for head and neck cancer radiotherapy: a randomized controlled trial

Despite modern treatment techniques, radiotherapy (RT) in patients with head and neck cancer (HNC) may be associated with high rates of acute and late treatment-related toxicity. The most effective approach to reduce sequelae after RT is to avoid as best as possible healthy tissues and organs at ris...

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Hauptverfasser: Held, Thomas (VerfasserIn) , Herpel, Christopher (VerfasserIn) , Schwindling, Franz Sebastian (VerfasserIn) , Christ, Leo (VerfasserIn) , Uzun-Lang, Kristin (VerfasserIn) , Regnery, Sebastian (VerfasserIn) , Eichkorn, Tanja (VerfasserIn) , Hommertgen, Adriane (VerfasserIn) , Jäkel, Cornelia (VerfasserIn) , Krisam, Johannes (VerfasserIn) , Moratin, Julius (VerfasserIn) , Mrosek, Jan Bernd (VerfasserIn) , Semmelmayer, Karl (VerfasserIn) , Plath, Karim (VerfasserIn) , Moutsis, Tracy Thecla (VerfasserIn) , Harrabi, Semi B. (VerfasserIn) , Herfarth, Klaus (VerfasserIn) , Freudlsperger, Christian (VerfasserIn) , Rammelsberg, Peter (VerfasserIn) , Debus, Jürgen (VerfasserIn) , Adeberg, Sebastian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 17 April 2021
In: Radiation oncology
Year: 2021, Jahrgang: 16, Pages: 1-8
ISSN:1748-717X
DOI:10.1186/s13014-021-01803-8
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13014-021-01803-8
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Verfasserangaben:Thomas Held, Christopher Herpel, Franz Sebastian Schwindling, Leo Christ, Kristin Lang, Sebastian Regnery, Tanja Eichkorn, Adriane Hommertgen, Cornelia Jaekel, Johannes Krisam, Julius Moratin, Jan Mrosek, Karl Metzger, Karim Zaoui, Tracy Moutsis, Semi Harrabi, Klaus Herfarth, Christian Freudlsperger, Peter Rammelsberg, Jürgen Debus and Sebastian Adeberg
Beschreibung
Zusammenfassung:Despite modern treatment techniques, radiotherapy (RT) in patients with head and neck cancer (HNC) may be associated with high rates of acute and late treatment-related toxicity. The most effective approach to reduce sequelae after RT is to avoid as best as possible healthy tissues and organs at risk from the radiation target volume. Even small geometric changes can lead to a significant dose reduction in normal tissue and better treatment tolerability. The major objective of the current study is to investigate 3D printed, tooth-borne tissue retraction devices (TRDs) compared to conventional dental splints for head and neck RT.
Beschreibung:Gesehen am 21.05.2021
Beschreibung:Online Resource
ISSN:1748-717X
DOI:10.1186/s13014-021-01803-8