3D-printed individualized tooth-borne tissue retraction devices compared to conventional dental splints for head and neck cancer radiotherapy: a randomized controlled trial
Despite modern treatment techniques, radiotherapy (RT) in patients with head and neck cancer (HNC) may be associated with high rates of acute and late treatment-related toxicity. The most effective approach to reduce sequelae after RT is to avoid as best as possible healthy tissues and organs at ris...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
17 April 2021
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| In: |
Radiation oncology
Year: 2021, Jahrgang: 16, Pages: 1-8 |
| ISSN: | 1748-717X |
| DOI: | 10.1186/s13014-021-01803-8 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13014-021-01803-8
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| Verfasserangaben: | Thomas Held, Christopher Herpel, Franz Sebastian Schwindling, Leo Christ, Kristin Lang, Sebastian Regnery, Tanja Eichkorn, Adriane Hommertgen, Cornelia Jaekel, Johannes Krisam, Julius Moratin, Jan Mrosek, Karl Metzger, Karim Zaoui, Tracy Moutsis, Semi Harrabi, Klaus Herfarth, Christian Freudlsperger, Peter Rammelsberg, Jürgen Debus and Sebastian Adeberg |
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| 245 | 1 | 0 | |a 3D-printed individualized tooth-borne tissue retraction devices compared to conventional dental splints for head and neck cancer radiotherapy |b a randomized controlled trial |c Thomas Held, Christopher Herpel, Franz Sebastian Schwindling, Leo Christ, Kristin Lang, Sebastian Regnery, Tanja Eichkorn, Adriane Hommertgen, Cornelia Jaekel, Johannes Krisam, Julius Moratin, Jan Mrosek, Karl Metzger, Karim Zaoui, Tracy Moutsis, Semi Harrabi, Klaus Herfarth, Christian Freudlsperger, Peter Rammelsberg, Jürgen Debus and Sebastian Adeberg |
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| 520 | |a Despite modern treatment techniques, radiotherapy (RT) in patients with head and neck cancer (HNC) may be associated with high rates of acute and late treatment-related toxicity. The most effective approach to reduce sequelae after RT is to avoid as best as possible healthy tissues and organs at risk from the radiation target volume. Even small geometric changes can lead to a significant dose reduction in normal tissue and better treatment tolerability. The major objective of the current study is to investigate 3D printed, tooth-borne tissue retraction devices (TRDs) compared to conventional dental splints for head and neck RT. | ||
| 650 | 4 | |a Intensity-modulated radiotherapy | |
| 650 | 4 | |a Particle therapy | |
| 650 | 4 | |a Radiation-induced oral mucositis | |
| 650 | 4 | |a Salivary gland tumor | |
| 650 | 4 | |a Squamous cell carcinoma | |
| 650 | 4 | |a Toxicity | |
| 650 | 4 | |a Xerostomia | |
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