A2BC-type porphyrin SAM on gold surface for bacteria detection applications: synthesis and surface functionalization
Currently used elaborate technologies for the detection of bacteria can be improved in regard to their time consumption, labor intensity, accuracy and reproducibility. Well-known electrical measurement methods might connect highly sensitive sensing systems with biological requirements. The developme...
Gespeichert in:
| Hauptverfasser: | , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
13 April 2021
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| In: |
Materials
Year: 2021, Jahrgang: 14, Heft: 8, Pages: 1-14 |
| ISSN: | 1996-1944 |
| DOI: | 10.3390/ma14081934 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/ma14081934 Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/1996-1944/14/8/1934 
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| Verfasserangaben: | Laurie Neumann, Lea Könemund, Valentina Rohnacher, Annemarie Pucci, Hans-Hermann Johannes and Wolfgang Kowalsky |
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| 520 | |a Currently used elaborate technologies for the detection of bacteria can be improved in regard to their time consumption, labor intensity, accuracy and reproducibility. Well-known electrical measurement methods might connect highly sensitive sensing systems with biological requirements. The development of modified sensor surfaces with self-assembled monolayers (SAMs) from functionalized porphyrin for bacteria trapping can lead to a highly sensitive sensor for bacteria detection. Different A2BC-type porphyrin structures were synthesized and examined regarding their optical behavior. We achieved the synthesis of a porphyrin for SAM formation on a gold surface as electrode material. Two possible bio linkers were attached on the opposite meso-position of the porphyrin, which allows the porphyrin to react as a linker on the surface for bacteria trapping. Different porphyrin structures were attached to a gold surface, the SAM formation and the respective coverage was investigated. | ||
| 650 | 4 | |a <i>E. coli</i> immobilization | |
| 650 | 4 | |a modified gold surface | |
| 650 | 4 | |a porphyrin | |
| 650 | 4 | |a SAM formation | |
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