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Biologically consistent dose accumulation using daily patient imaging

This work addresses a basic inconsistency in the way dose is accumulated in radiotherapy when predicting the biological effect based on the linear quadratic model (LQM). To overcome this inconsistency, we introduce and evaluate the concept of the total biological dose, bEQDd.

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Bibliographic Details
Main Authors: Niebuhr, Nina Isabelle (Author) , Splinter, Mona (Author) , Bostel, Tilman (Author) , Seco, Joao (Author) , Hentschke, Clemens M. (Author) , Floca, Ralf (Author) , Hörner-Rieber, Juliane (Author) , Alber, Markus (Author) , Huber, Peter E. (Author) , Nicolay, Nils (Author) , Pfaffenberger, Asja (Author)
Format: Article (Journal)
Language:English
Published: 06 April 2021
In: Radiation oncology
Year: 2021, Volume: 16, Pages: 1-16
ISSN:1748-717X
DOI:10.1186/s13014-021-01789-3
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13014-021-01789-3
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Author Notes:Nina I. Niebuhr, Mona Splinter, Tilman Bostel, Joao Seco, Clemens M. Hentschke, Ralf O. Floca, Juliane Hörner-Rieber, Markus Alber, Peter Huber, Nils H. Nicolay and Asja Pfaffenberger
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Summary:This work addresses a basic inconsistency in the way dose is accumulated in radiotherapy when predicting the biological effect based on the linear quadratic model (LQM). To overcome this inconsistency, we introduce and evaluate the concept of the total biological dose, bEQDd.
Item Description:Gesehen am 04.06.2021
Physical Description:Online Resource
ISSN:1748-717X
DOI:10.1186/s13014-021-01789-3

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