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Multiple glutathione disulfide removal pathways mediate cytosolic redox homeostasis

Quantification of cytosolic glutathione redox potential leads to the discovery that the ABC-C transporter Ycf1 rapidly transports oxidized glutathione (GSSG) into vacuoles and whole-cell GSSG should not be used as a proxy for cytosolic GSSG.

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Bibliographic Details
Main Authors: Morgan, Bruce (Author) , Ezeriņa, Daria (Author) , Amoako, Theresa N. E. (Author) , Riemer, Jan (Author) , Seedorf, Matthias (Author) , Dick, Tobias P. (Author)
Format: Article (Journal)
Language:English
Published: 2013
In: Nature chemical biology
Year: 2012, Volume: 9, Issue: 2, Pages: 119-125
ISSN:1552-4469
DOI:10.1038/nchembio.1142
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nchembio.1142
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nchembio.1142
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Author Notes:Bruce Morgan, Daria Ezeriņa, Theresa N.E. Amoako, Jan Riemer, Matthias Seedorf & Tobias P. Dick

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