Autofluorescence-guided surgery for the treatment of medication-related osteonecrosis of the jaw (MRONJ): a retrospective single-center study
Objective - Medication-related osteonecrosis of the jaw (MRONJ) has become a serious concern for patients under antiresorptive treatment, especially in the oncological setting. Different approaches have been described in the management of MRONJ, including innovative autofluorescence-guided surgery....
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| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2021
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| In: |
Oral surgery, oral medicine, oral pathology and oral radiology
Year: 2021, Jahrgang: 131, Heft: 5, Pages: 519-526 |
| ISSN: | 2212-4411 |
| DOI: | 10.1016/j.oooo.2020.10.018 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.oooo.2020.10.018 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S2212440320312918 
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| Verfasserangaben: | Sven Otto, Eva Maria Schnödt, Selgai Haidari, Teresa Franziska Brunner, Suad Aljohani, Mohamed Mosleh, Oliver Ristow, Matthias Troeltzsch, Christoph Pautke, Michael Ehrenfeld and Riham Fliefel |
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| 245 | 1 | 0 | |a Autofluorescence-guided surgery for the treatment of medication-related osteonecrosis of the jaw (MRONJ) |b a retrospective single-center study |c Sven Otto, Eva Maria Schnödt, Selgai Haidari, Teresa Franziska Brunner, Suad Aljohani, Mohamed Mosleh, Oliver Ristow, Matthias Troeltzsch, Christoph Pautke, Michael Ehrenfeld and Riham Fliefel |
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| 520 | |a Objective - Medication-related osteonecrosis of the jaw (MRONJ) has become a serious concern for patients under antiresorptive treatment, especially in the oncological setting. Different approaches have been described in the management of MRONJ, including innovative autofluorescence-guided surgery. However, until now, there has been a lack of data regarding the outcome. In this study, we evaluated the efficacy of minimally invasive autofluorescence-guided resection in MRONJ. - Study Design - Seventy-five patients with 82 lesions were included in this retrospective, single-center study. All included patients were diagnosed with MRONJ according to the American Association of Oral and Maxillofacial Surgeons guidelines and underwent autofluorescence-guided surgery with a minimum follow-up of 3 months. The primary outcome was complete integrity of the mucosa and absence of bone exposure. - Results - The MRONJ stages were stage 0 (3.7%), stage 1 (3.7%), stage 2 (75.6%), and stage 3 (17%). Overall, complete mucosal healing of all lesions after the first surgery was 81.7% (67 of 82), whereas it was 90.2% (74 of 82) after revision surgery. - Conclusions - The study showed that autofluorescence-guided surgery is a safe and successful treatment option that can be considered for all stages of MRONJ. | ||
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