Serum GFAP and NfL as disease severity and prognostic biomarkers in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder

Neuromyelitis optica spectrum disorder (NMOSD) is a frequently disabling neuroinflammatory syndrome with a relapsing course. Blood-based disease severity and prognostic biomarkers for NMOSD are a yet unmet clinical need. Here, we evaluated serum glial fibrillary acidic protein (sGFAP) and neurofilam...

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Main Authors:	Schindler, Patrick (Author) , Grittner, Ulrike (Author) , Oechtering, Johanna (Author) , Leppert, David (Author) , Siebert, Nadja (Author) , Duchow, Ankelien S. (Author) , Oertel, Frederike Cosima (Author) , Asseyer, Susanna (Author) , Kuchling, Joseph (Author) , Zimmermann, Hanna (Author) , Brandt, Alexander Ulrich (Author) , Benkert, Pascal (Author) , Reindl, Markus (Author) , Jarius, Sven (Author) , Paul, Friedemann (Author) , Bellmann-Strobl, Judith (Author) , Kuhle, Jens (Author) , Ruprecht, Klemens (Author)
Format:	Article (Journal)
Language:	English
Published:	01 May 2021
In:	Journal of neuroinflammation Year: 2021, Volume: 18, Pages: 1-14
ISSN:	1742-2094
DOI:	10.1186/s12974-021-02138-7
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12974-021-02138-7
Author Notes:	Patrick Schindler, Ulrike Grittner, Johanna Oechtering, David Leppert, Nadja Siebert, Ankelien S. Duchow, Frederike C. Oertel, Susanna Asseyer, Joseph Kuchling, Hanna G. Zimmermann, Alexander U. Brandt, Pascal Benkert, Markus Reindl, Sven Jarius, Friedemann Paul, Judith Bellmann-Strobl, Jens Kuhle and Klemens Ruprecht