Serum GFAP and NfL as disease severity and prognostic biomarkers in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder
Neuromyelitis optica spectrum disorder (NMOSD) is a frequently disabling neuroinflammatory syndrome with a relapsing course. Blood-based disease severity and prognostic biomarkers for NMOSD are a yet unmet clinical need. Here, we evaluated serum glial fibrillary acidic protein (sGFAP) and neurofilam...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
01 May 2021
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| In: |
Journal of neuroinflammation
Year: 2021, Jahrgang: 18, Pages: 1-14 |
| ISSN: | 1742-2094 |
| DOI: | 10.1186/s12974-021-02138-7 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12974-021-02138-7
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| Verfasserangaben: | Patrick Schindler, Ulrike Grittner, Johanna Oechtering, David Leppert, Nadja Siebert, Ankelien S. Duchow, Frederike C. Oertel, Susanna Asseyer, Joseph Kuchling, Hanna G. Zimmermann, Alexander U. Brandt, Pascal Benkert, Markus Reindl, Sven Jarius, Friedemann Paul, Judith Bellmann-Strobl, Jens Kuhle and Klemens Ruprecht |
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| 245 | 1 | 0 | |a Serum GFAP and NfL as disease severity and prognostic biomarkers in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder |c Patrick Schindler, Ulrike Grittner, Johanna Oechtering, David Leppert, Nadja Siebert, Ankelien S. Duchow, Frederike C. Oertel, Susanna Asseyer, Joseph Kuchling, Hanna G. Zimmermann, Alexander U. Brandt, Pascal Benkert, Markus Reindl, Sven Jarius, Friedemann Paul, Judith Bellmann-Strobl, Jens Kuhle and Klemens Ruprecht |
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| 520 | |a Neuromyelitis optica spectrum disorder (NMOSD) is a frequently disabling neuroinflammatory syndrome with a relapsing course. Blood-based disease severity and prognostic biomarkers for NMOSD are a yet unmet clinical need. Here, we evaluated serum glial fibrillary acidic protein (sGFAP) and neurofilament light (sNfL) as disease severity and prognostic biomarkers in patients with aquaporin-4 immunoglobulin (Ig)G positive (AQP4-IgG+) NMOSD. | ||
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