Role of synaptophysin, chromogranin and CD56 in adenocarcinoma and squamous cell carcinoma of the lung lacking morphological features of neuroendocrine differentiation: a retrospective large-scale study on 1170 tissue samples
Synaptophysin, chromogranin and CD56 are recommended markers to identify pulmonary tumors with neuroendocrine differentiation. Whether the expression of these markers in pulmonary adenocarcinoma and pulmonary squamous cell carcinoma is a prognostic factor has been a matter of debate. Therefore, we i...
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| Hauptverfasser: | , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
01 May 2021
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| In: |
BMC cancer
Year: 2021, Jahrgang: 21, Pages: 1-9 |
| ISSN: | 1471-2407 |
| DOI: | 10.1186/s12885-021-08140-9 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12885-021-08140-9 Verlag, kostenfrei, Volltext: https://bmccancer.biomedcentral.com/articles/10.1186/s12885-021-08140-9 
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| Verfasserangaben: | Katharina Kriegsmann, Christiane Zgorzelski, Thomas Muley, Petros Christopoulos, Michael Thomas, Hauke Winter, Martin Eichhorn, Florian Eichhorn, Moritz von Winterfeld, Esther Herpel, Benjamin Goeppert, Albrecht Stenzinger, Felix J.F. Herth, Arne Warth and Mark Kriegsmann |
MARC
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| 245 | 1 | 0 | |a Role of synaptophysin, chromogranin and CD56 in adenocarcinoma and squamous cell carcinoma of the lung lacking morphological features of neuroendocrine differentiation |b a retrospective large-scale study on 1170 tissue samples |c Katharina Kriegsmann, Christiane Zgorzelski, Thomas Muley, Petros Christopoulos, Michael Thomas, Hauke Winter, Martin Eichhorn, Florian Eichhorn, Moritz von Winterfeld, Esther Herpel, Benjamin Goeppert, Albrecht Stenzinger, Felix J.F. Herth, Arne Warth and Mark Kriegsmann |
| 246 | 3 | 3 | |a Role of synaptophysin, chromogranin and CD fifty-six in adenocarcinoma and squamous cell carcinoma of the lung lacking morphological features of neuroendocrine differentiation |
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| 520 | |a Synaptophysin, chromogranin and CD56 are recommended markers to identify pulmonary tumors with neuroendocrine differentiation. Whether the expression of these markers in pulmonary adenocarcinoma and pulmonary squamous cell carcinoma is a prognostic factor has been a matter of debate. Therefore, we investigated retrospectively a large cohort to expand the data on the role of synaptophysin, chromogranin and CD56 in non-small cell lung cancer lacking morphological features of neuroendocrine differentiation. | ||
| 650 | 4 | |a CD56 | |
| 650 | 4 | |a Chromogranin | |
| 650 | 4 | |a Immunohistochemistry | |
| 650 | 4 | |a Non-small cell lung cancer | |
| 650 | 4 | |a Synaptophysin | |
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