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Longitudinal changes of cognitive deficits and treatment outcome of cognitive behavioral therapy for major depression

The current study examined neuropsychological changes over the course of cognitive behavioral therapy (CBT) in outpatients with major depressive disorder and the influence of cognitive deficits as predictors of clinical outcome in depression. A neuropsychological test battery was carried out on depr...

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Bibliographic Details
Main Authors: Bernhardt, Maren (Author) , Schwert, Christine (Author) , Aschenbrenner, Steffen (Author) , Weisbrod, Matthias (Author) , Schröder, Annette (Author)
Format: Article (Journal)
Language:English
Published: 2021
In: The journal of nervous and mental disease
Year: 2021, Volume: 209, Issue: 5, Pages: 336-342
ISSN:1539-736X
DOI:10.1097/NMD.0000000000001301
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/NMD.0000000000001301
Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/jonmd/Abstract/2021/05000/Longitudinal_Changes_of_Cognitive_Deficits_and.5.aspx
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Author Notes:Maren Bernhardt, Christine Schwert, Steffen Aschenbrenner, Matthias Weisbrod, Annette Schröder
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Summary:The current study examined neuropsychological changes over the course of cognitive behavioral therapy (CBT) in outpatients with major depressive disorder and the influence of cognitive deficits as predictors of clinical outcome in depression. A neuropsychological test battery was carried out on depressed outpatients (N = 54) at the beginning and at the end of CBT. Small improvements were found in divided attention, figural memory, and processing speed from pre- to posttreatment. Cognitive deficits in executive functions before treatment predicted the clinical outcome at the end of CBT. The present study reveals that attention and memory deficits are most likely to improve over the course of treatment, whereas executive functions remain stable in the long term. Depressed patients with worse executive functions at the beginning of treatment seem to benefit more from long-term CBT therapy.
Item Description:Gesehen am 25.06.2021
Physical Description:Online Resource
ISSN:1539-736X
DOI:10.1097/NMD.0000000000001301

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