Feasibility of 6-month maintenance cetuximab after adjuvant concurrent chemoradiation plus cetuximab in squamous cell carcinoma of the head and neck
Close resection margins < 5 mm (CM) or extra capsular extent at the lymph nodes (ECE) impair the prognosis of patients with squamous cell cancer of the head and neck (SCCHN) scheduled for adjuvant radiochemotherapy. We conducted a multicenter phase II study to investigate toxicity and efficacy of...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
5 July 2013
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| In: |
Strahlentherapie und Onkologie
Year: 2013, Jahrgang: 189, Heft: 8, Pages: 625-631 |
| ISSN: | 1439-099X |
| DOI: | 10.1007/s00066-013-0378-2 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00066-013-0378-2
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| Verfasserangaben: | C. Matuschek, E. Bölke, C. Belka, U. Ganswindt, M. Henke, P. Stegmaier, M. Bamberg, S. Welz, J. Debus, A. Gioules, A. Voigt, G. Volk, C. Ohmann, T. Wiegel, V. Budach, M. Stuschke, J. Schipper, P.A. Gerber, W. Budach |
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| 520 | |a Close resection margins < 5 mm (CM) or extra capsular extent at the lymph nodes (ECE) impair the prognosis of patients with squamous cell cancer of the head and neck (SCCHN) scheduled for adjuvant radiochemotherapy. We conducted a multicenter phase II study to investigate toxicity and efficacy of additional cetuximab administered concomitantly and as maintenance for the duration of 6 months following adjuvant radiochemotherapy., Ppreliminary results on feasibility and acute toxicity on skin and mucosa are presented in this article. | ||
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