Reconstruction of full thickness defects on the scalp with artificial dermal regeneration template: Analysis of long-term results in 68 cases

BACKGROUND - Artificial skin substitute templates have been shown to be a reliable solution for the reconstruction of large scalp defects with exposed skull bone, but there is a lack of long-term data. OBJECTIVE - The aim of this retrospective study was to investigate the long-term outcome of the pr...

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Hauptverfasser: Benecke, Johannes (VerfasserIn) , Koenen, Wolfgang (VerfasserIn) , Mager, Lisa Marie (VerfasserIn) , Weina, Kasia (VerfasserIn) , Klemke, Claus-Detlev (VerfasserIn) , Felcht, Moritz (VerfasserIn) , Faulhaber, Jörg (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: January 2021
In: Dermatologic surgery
Year: 2021, Jahrgang: 47, Heft: 1, Pages: e1-e4
ISSN:1524-4725
DOI:10.1097/DSS.0000000000002448
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/DSS.0000000000002448
Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/dermatologicsurgery/Abstract/2021/01000/Reconstruction_of_Full_Thickness_Defects_on_the.7.aspx
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Verfasserangaben:Benecke, Johannes; Koenen, Wolfgang; Mager, Lisa; Weina, Kasia; Klemke, Claus-Detlev; Felcht, Moritz; Faulhaber, Jörg

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520 |a BACKGROUND - Artificial skin substitute templates have been shown to be a reliable solution for the reconstruction of large scalp defects with exposed skull bone, but there is a lack of long-term data. OBJECTIVE - The aim of this retrospective study was to investigate the long-term outcome of the procedure in a large cohort of 68 cases. MATERIALS AND METHODS - In total, 58 patients with 68 full thickness scalp defects with exposed skull bone, were included. Mean follow-up time was 24 (±19) months. RESULTS - The mean size of the defects was 63 (±54) cm2. During the follow-up period, no local recurrences occurred. Complications were observed in 13% of the cases including template necrosis (4%), infections (4%), ulcerations (3%), and autograft necrosis (2%). During the final follow-up, 26 patients had died due to internal diseases not associated with the surgery. Cosmetic results were rated good by the patients and an independent observer. CONCLUSION - The use of a dermal regeneration template for the reconstruction of large, full thickness defects of the scalp with exposed skull bone is a reliable method regarding the complication rate, safety of the procedure, and cosmetic outcome. Limitations of this study are the retrospective and single center design. 
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