Buchumschlag

Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations

Soft-tissue sarcomas (STS) are a heterogeneous group of mesenchymal tumors for which response to immunotherapies is not well established. Therefore, it is important to risk-stratify and identify STS patients who will most likely benefit from these treatments.

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Bibliographische Detailangaben
Hauptverfasser: Simon, Malte (VerfasserIn) , Mughal, Sadaf Shabbir (VerfasserIn) , Horak, Peter (VerfasserIn) , Uhrig, Sebastian (VerfasserIn) , Buchloh, Jonas (VerfasserIn) , Aybey, Bogac (VerfasserIn) , Stenzinger, Albrecht (VerfasserIn) , Glimm, Hanno (VerfasserIn) , Fröhling, Stefan (VerfasserIn) , Brors, Benedikt (VerfasserIn) , Imbusch, Charles (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: May 12 2021
In: Journal of translational medicine
Year: 2021, Jahrgang: 19, Pages: 1-17
ISSN:1479-5876
DOI:10.1186/s12967-021-02858-7
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12967-021-02858-7
Volltext
Verfasserangaben:Malte Simon, Sadaf S. Mughal, Peter Horak, Sebastian Uhrig, Jonas Buchloh, Bogac Aybey, Albrecht Stenzinger, Hanno Glimm, Stefan Fröhling, Benedikt Brors and Charles D. Imbusch
Beschreibung
Zusammenfassung:Soft-tissue sarcomas (STS) are a heterogeneous group of mesenchymal tumors for which response to immunotherapies is not well established. Therefore, it is important to risk-stratify and identify STS patients who will most likely benefit from these treatments.
Beschreibung:Gesehen am 20.07.2021
Beschreibung:Online Resource
ISSN:1479-5876
DOI:10.1186/s12967-021-02858-7

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