Endoreplication

Developmentally programmed polyploidy occurs by at least four different mechanisms, two of which (endoreduplication and endomitosis) involve switching from mitotic cell cycles to endocycles by the selective loss of mitotic cyclin-dependent kinase (CDK) activity and bypassing many of the processes of...

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Hauptverfasser: Zielke, Norman (VerfasserIn) , Edgar, Bruce (VerfasserIn) , DePamphilis, Melvin L. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2013
In: Cold Spring Harbor perspectives in biology
Year: 2013, Jahrgang: 5, Heft: 1, Pages: 1-16
ISSN:1943-0264
DOI:10.1101/cshperspect.a012948
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1101/cshperspect.a012948
Verlag, lizenzpflichtig, Volltext: http://cshperspectives.cshlp.org/content/5/1/a012948
Volltext
Verfasserangaben:Norman Zielke, Bruce A. Edgar, and Melvin L. DePamphilis
Beschreibung
Zusammenfassung:Developmentally programmed polyploidy occurs by at least four different mechanisms, two of which (endoreduplication and endomitosis) involve switching from mitotic cell cycles to endocycles by the selective loss of mitotic cyclin-dependent kinase (CDK) activity and bypassing many of the processes of mitosis. Here we review the mechanisms of endoreplication, focusing on recent results from Drosophila and mice.
Beschreibung:Gesehen am 28.07.2021
Beschreibung:Online Resource
ISSN:1943-0264
DOI:10.1101/cshperspect.a012948