Buchumschlag

A disulfide-constrained miniprotein with striking tumor-binding specificity developed by ribosome display

Fold me to hold me: A specific binding agent against the delta-like ligand 4 protein, which is expressed in angiogenesis, was identified by ribosome display. Specific tumor binding of this molecular imaging agent depends on the appropriate disulfide connectivity of its scaffold.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zoller, Frederic (VerfasserIn) , Hebling, Ulrike (VerfasserIn) , Altmann, Annette (VerfasserIn) , Lindner, Thomas (VerfasserIn) , Mier, Walter (VerfasserIn) , Haberkorn, Uwe (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 20 September 2013
In: Angewandte Chemie. International edition
Year: 2013, Jahrgang: 52, Heft: 45, Pages: 11760-11764
ISSN:1521-3773
DOI:10.1002/anie.201304603
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/anie.201304603
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201304603
Volltext
Verfasserangaben:Frederic Zoller, Annette Markert, Philippe Barthe, Ulrike Hebling, Annette Altmann, Thomas Lindner, Walter Mier, and Uwe Haberkorn

MARC

LEADER 00000caa a2200000 c 4500
001 1765225744
003 DE-627
005 20230427153455.0
007 cr uuu---uuuuu
008 210802s2013 xx |||||o 00| ||eng c
024 7 |a 10.1002/anie.201304603  |2 doi 
035 |a (DE-627)1765225744 
035 |a (DE-599)KXP1765225744 
035 |a (OCoLC)1341420030 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Zoller, Frederic  |e VerfasserIn  |0 (DE-588)1029423016  |0 (DE-627)73354410X  |0 (DE-576)377282553  |4 aut 
245 1 2 |a A disulfide-constrained miniprotein with striking tumor-binding specificity developed by ribosome display  |c Frederic Zoller, Annette Markert, Philippe Barthe, Ulrike Hebling, Annette Altmann, Thomas Lindner, Walter Mier, and Uwe Haberkorn 
264 1 |c 20 September 2013 
300 |a 5 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 02.08.2021 
520 |a Fold me to hold me: A specific binding agent against the delta-like ligand 4 protein, which is expressed in angiogenesis, was identified by ribosome display. Specific tumor binding of this molecular imaging agent depends on the appropriate disulfide connectivity of its scaffold. 
650 4 |a molecular imaging 
650 4 |a peptide folding 
650 4 |a protein design 
650 4 |a ribosome display 
650 4 |a solid-phase synthesis 
700 1 |a Hebling, Ulrike  |e VerfasserIn  |0 (DE-588)1238031935  |0 (DE-627)1765226325  |4 aut 
700 1 |a Altmann, Annette  |e VerfasserIn  |0 (DE-588)1032267984  |0 (DE-627)738189111  |0 (DE-576)379930099  |4 aut 
700 1 |a Lindner, Thomas  |e VerfasserIn  |0 (DE-588)107520318X  |0 (DE-627)833005804  |0 (DE-576)443314772  |4 aut 
700 1 |a Mier, Walter  |d 1966-  |e VerfasserIn  |0 (DE-588)12029026X  |0 (DE-627)69653567X  |0 (DE-576)292141599  |4 aut 
700 1 |a Haberkorn, Uwe  |d 1959-  |e VerfasserIn  |0 (DE-588)1022913905  |0 (DE-627)717331245  |0 (DE-576)366166352  |4 aut 
773 0 8 |i Enthalten in  |t Angewandte Chemie. International edition  |d Weinheim : Wiley-VCH, 1998  |g 52(2013), 45, Seite 11760-11764  |h Online-Ressource  |w (DE-627)320497879  |w (DE-600)2011836-3  |w (DE-576)111552060  |x 1521-3773  |7 nnas  |a A disulfide-constrained miniprotein with striking tumor-binding specificity developed by ribosome display 
773 1 8 |g volume:52  |g year:2013  |g number:45  |g pages:11760-11764  |g extent:5  |a A disulfide-constrained miniprotein with striking tumor-binding specificity developed by ribosome display 
856 4 0 |u https://doi.org/10.1002/anie.201304603  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201304603  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20210802 
993 |a Article 
994 |a 2013 
998 |g 1022913905  |a Haberkorn, Uwe  |m 1022913905:Haberkorn, Uwe  |d 910000  |d 911400  |e 910000PH1022913905  |e 911400PH1022913905  |k 0/910000/  |k 1/910000/911400/  |p 8  |y j 
998 |g 12029026X  |a Mier, Walter  |m 12029026X:Mier, Walter  |d 910000  |d 911400  |d 140000  |e 910000PM12029026X  |e 911400PM12029026X  |e 140000PM12029026X  |k 0/910000/  |k 1/910000/911400/  |k 0/140000/  |p 7 
998 |g 107520318X  |a Lindner, Thomas  |m 107520318X:Lindner, Thomas  |d 910000  |d 911400  |e 910000PL107520318X  |e 911400PL107520318X  |k 0/910000/  |k 1/910000/911400/  |p 6 
998 |g 1032267984  |a Altmann, Annette  |m 1032267984:Altmann, Annette  |d 910000  |d 911400  |e 910000PA1032267984  |e 911400PA1032267984  |k 0/910000/  |k 1/910000/911400/  |p 5 
998 |g 1238031935  |a Hebling, Ulrike  |m 1238031935:Hebling, Ulrike  |d 50000  |e 50000PH1238031935  |k 0/50000/  |p 4 
999 |a KXP-PPN1765225744  |e 3959129467 
BIB |a Y 
SER |a journal 
JSO |a {"note":["Gesehen am 02.08.2021"],"recId":"1765225744","person":[{"given":"Frederic","display":"Zoller, Frederic","role":"aut","family":"Zoller"},{"family":"Hebling","role":"aut","given":"Ulrike","display":"Hebling, Ulrike"},{"family":"Altmann","role":"aut","display":"Altmann, Annette","given":"Annette"},{"given":"Thomas","display":"Lindner, Thomas","role":"aut","family":"Lindner"},{"display":"Mier, Walter","given":"Walter","role":"aut","family":"Mier"},{"display":"Haberkorn, Uwe","given":"Uwe","role":"aut","family":"Haberkorn"}],"language":["eng"],"name":{"displayForm":["Frederic Zoller, Annette Markert, Philippe Barthe, Ulrike Hebling, Annette Altmann, Thomas Lindner, Walter Mier, and Uwe Haberkorn"]},"origin":[{"dateIssuedDisp":"20 September 2013","dateIssuedKey":"2013"}],"relHost":[{"recId":"320497879","title":[{"title":"Angewandte Chemie","subtitle":"a journal of the Gesellschaft Deutscher Chemiker","title_sort":"Angewandte Chemie","partname":"International edition"}],"physDesc":[{"extent":"Online-Ressource"}],"id":{"doi":["10.1002/(ISSN)1521-3773"],"zdb":["2011836-3"],"issn":["1521-3773"],"eki":["320497879"]},"origin":[{"publisher":"Wiley-VCH","dateIssuedDisp":"1998-","dateIssuedKey":"1998","publisherPlace":"Weinheim"}],"language":["eng"],"part":{"volume":"52","year":"2013","text":"52(2013), 45, Seite 11760-11764","issue":"45","extent":"5","pages":"11760-11764"},"note":["Gesehen am 20.12.2022","Fortsetzung der Druck-Ausgabe"],"pubHistory":["37.1998 -"],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"A disulfide-constrained miniprotein with striking tumor-binding specificity developed by ribosome displayAngewandte Chemie. International edition","corporate":[{"role":"isb","display":"Gesellschaft Deutscher Chemiker"}],"titleAlt":[{"title":"Angewandte Chemie / International edition"}]}],"id":{"doi":["10.1002/anie.201304603"],"eki":["1765225744"]},"physDesc":[{"extent":"5 S."}],"title":[{"title":"A disulfide-constrained miniprotein with striking tumor-binding specificity developed by ribosome display","title_sort":"disulfide-constrained miniprotein with striking tumor-binding specificity developed by ribosome display"}],"type":{"media":"Online-Ressource","bibl":"article-journal"}} 
SRT |a ZOLLERFREDDISULFIDEC2020 

Ähnliche Einträge