Conformation and activity of glucose oxidase on homogeneously coated and nanostructured surfaces
Protein unfolding and loss of protein function upon surface contact is a major problem in biotechnology and biomedicine. Using glucose oxidase (GOx) as a model protein, we investigated the impact of surface chemistry, topography, and confinement on enzyme activity, conformation, and affinity. A part...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
May 17, 2013
|
| In: |
The journal of physical chemistry. B, Biophysics, biomaterials, liquids, and soft matter
Year: 2013, Volume: 117, Issue: 23, Pages: 6980-6989 |
| ISSN: | 1520-5207 |
| DOI: | 10.1021/jp401906h |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1021/jp401906h
|
| Author Notes: | A. Seehuber and R. Dahint |
Search Result 1
Search Result 2