GRN, NOTCH3, FN1, and PINK1 expression in eutopic endometrium: potential biomarkers in the detection of endometriosis - a pilot study
Endometriosis (EM) is a common gynecological disease affecting 10-15% of women of reproductive age. However, molecular mechanisms and pathogenesis are still not completely understood. Furthermore, due to the absence of a reliable clinical biomarker, the only viable method for the often-delayed defin...
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| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
07 October 2020
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| In: |
Journal of assisted reproduction and genetics
Year: 2020, Jahrgang: 37, Heft: 11, Pages: 2723-2732 |
| ISSN: | 1573-7330 |
| DOI: | 10.1007/s10815-020-01905-4 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s10815-020-01905-4
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| Verfasserangaben: | Isabell Holzer, Amanda Machado Weber, Anne Marshall, Alexander Freis, Julia Jauckus, Thomas Strowitzki, Ariane Germeyer |
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| 520 | |a Endometriosis (EM) is a common gynecological disease affecting 10-15% of women of reproductive age. However, molecular mechanisms and pathogenesis are still not completely understood. Furthermore, due to the absence of a reliable clinical biomarker, the only viable method for the often-delayed definitive diagnosis is laparoscopic surgery. Our objective was to analyze molecular differences of selected endometrial proteins and genes of women suffering from different stages of EM compared with healthy women to evaluate potential clinical biomarkers. | ||
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