Buchumschlag

An increased bone mineral density is an adverse prognostic factor in patients with systemic mastocytosis

Systemic mastocytosis (SM) is characterized by the expansion of clonal mast cells that infiltrate various organ systems. The extent of organ infiltration and subsequent organ damage distinguishes between indolent SM (ISM) defined by a nearly normal life expectancy and advanced SM (AdvSM) defined by...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Riffel, Philipp (VerfasserIn) , Schwaab, Juliana (VerfasserIn) , Lutz, Christopher (VerfasserIn) , Naumann, Nicole (VerfasserIn) , Metzgeroth, Georgia (VerfasserIn) , Fabarius, Alice (VerfasserIn) , Schönberg, Stefan (VerfasserIn) , Hofmann, Wolf-Karsten (VerfasserIn) , Valent, Peter (VerfasserIn) , Reiter, Andreas (VerfasserIn) , Jawhar, Mohamad (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 24 January 2020
In: Journal of cancer research and clinical oncology
Year: 2020, Jahrgang: 146, Heft: 4, Pages: 945-951
ISSN:1432-1335
DOI:10.1007/s00432-019-03119-3
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00432-019-03119-3
Volltext
Verfasserangaben:Philipp Riffel, Juliana Schwaab, Christopher Lutz, Nicole Naumann, Georgia Metzgeroth, Alice Fabarius, Stefan O. Schoenberg, Wolf-Karsten Hofmann, Peter Valent, Andreas Reiter, Mohamad Jawhar
Beschreibung
Zusammenfassung:Systemic mastocytosis (SM) is characterized by the expansion of clonal mast cells that infiltrate various organ systems. The extent of organ infiltration and subsequent organ damage distinguishes between indolent SM (ISM) defined by a nearly normal life expectancy and advanced SM (AdvSM) defined by poor prognosis. In ISM, measurement of the bone mineral density (BMD) frequently reveals osteoporosis. In contrast, the clinical implication of an increased BMD and osteosclerosis remains unclear.
Beschreibung:Gesehen am 01.09.2021
Beschreibung:Online Resource
ISSN:1432-1335
DOI:10.1007/s00432-019-03119-3

Ähnliche Einträge