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The adoptr package: adaptive optimal designs for clinical trials in R

Even though adaptive two-stage designs with unblinded interim analyses are becoming increasingly popular in clinical trial designs, there is a lack of statistical software to make their application more straightforward. The package adoptr fills this gap for the common case of two-stage one- or two-a...

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Bibliographic Details
Main Authors: Kunzmann, Kevin (Author) , Pilz, Maximilian (Author) , Herrmann, Carolin (Author) , Rauch, Geraldine (Author) , Kieser, Meinhard (Author)
Format: Article (Journal)
Language:English
Published: 2021-06-28
In: Journal of statistical software
Year: 2021, Volume: 98, Issue: 9, Pages: 1-21
ISSN:1548-7660
DOI:10.18637/jss.v098.i09
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.18637/jss.v098.i09
Verlag, lizenzpflichtig, Volltext: https://www.jstatsoft.org/index.php/jss/article/view/v098i09
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Author Notes:Kevin Kunzmann, Maximilian Pilz, Carolin Herrmann, Geraldine Rauch, Meinhard Kieser

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