Post-induction treatment for acute myeloid leukemia: something change?

Until recently, improvement in terms of survival for patients with acute myeloid leukemia (AML) was achieved mostly in younger patients with dose intensification of conventional chemotherapy and a broadening use of allogeneic hematopoietic cell transplantation (allo-HCT) whereas the results remained...

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Hauptverfasser: Jaramillo Segura, Sonia (VerfasserIn) , Schlenk, Richard Friedrich (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 16 July 2021
In: Current oncology reports
Year: 2021, Jahrgang: 23, Heft: 9
ISSN:1534-6269
DOI:10.1007/s11912-021-01092-0
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s11912-021-01092-0
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Verfasserangaben:Sonia Jaramillo, Richard F. Schlenk
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Zusammenfassung:Until recently, improvement in terms of survival for patients with acute myeloid leukemia (AML) was achieved mostly in younger patients with dose intensification of conventional chemotherapy and a broadening use of allogeneic hematopoietic cell transplantation (allo-HCT) whereas the results remained dismal and very stable in patients older than 60 years. The current review highlights the recent developments in standard intensive post-remission chemotherapy, evidence for the use of recently approved agents, and discusses the relevance of measurable residual disease (MRD) measurement in treatment adaptation.
Beschreibung:Gesehen am 23.09.2021
Beschreibung:Online Resource
ISSN:1534-6269
DOI:10.1007/s11912-021-01092-0