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Mandibular brown tumor as a result of secondary hyperparathyroidism: a case report with 5 years follow-up and review of the literature

Background: Brown tumor is a rare skeletal manifestation of secondary hyperparathyroidism. Although diagnosis of the disease is increasingly seen in early stages due to improved screening techniques, some patients still present in a progressed disease stage. The treatment depends on tumor mass and v...

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Main Authors: Shavlokhova, Veronika (Author) , Goeppert, Benjamin (Author) , Gaida, Matthias (Author) , Saravi, Babak Ebrahimzadeh (Author) , Bouffleur, Frederic (Author) , Vollmer, Andreas (Author) , Vollmer, Michael (Author) , Freudlsperger, Christian (Author) , Mertens, Christian (Author) , Hoffmann, Jürgen (Author)
Format: Article (Journal)
Language:English
Published: 9 July 2021
In: International journal of environmental research and public health
Year: 2021, Volume: 18, Issue: 14, Pages: 1-11
ISSN:1660-4601
DOI:10.3390/ijerph18147370
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/ijerph18147370
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/1660-4601/18/14/7370
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Author Notes:Veronika Shavlokhova, Benjamin Goeppert, Matthias M. Gaida, Babak Saravi, Frederic Weichel, Andreas Vollmer, Michael Vollmer, Christian Freudlsperger, Christian Mertens and Jürgen Hoffmann
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Summary:Background: Brown tumor is a rare skeletal manifestation of secondary hyperparathyroidism. Although diagnosis of the disease is increasingly seen in early stages due to improved screening techniques, some patients still present in a progressed disease stage. The treatment depends on tumor mass and varies from a conservative approach with supportive parathyroidectomy to extensive surgical resection with subsequent reconstruction. Case presentation: We report a case of extensive mandibular brown tumor in a patient with a history of systemic lupus erythematosus, chronic kidney disease, and secondary hyperparathyroidism. Following radical resection of the affected bone, reconstruction could be successfully performed using a free flap. Conclusions: There were no signs of recurrence during five years of close follow-up. Increased awareness and multidisciplinary follow-ups could allow early diagnosis and prevent the need for radical therapeutical approaches.
Item Description:Gesehen am 23.09.2021
Physical Description:Online Resource
ISSN:1660-4601
DOI:10.3390/ijerph18147370

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