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Using chromatogram averaging to improve quantitation of minor impurities

Averaging of chromatograms can lead to enhancement of signal to noise ratio (S/N) in proportion to the square root of the number of measurements. Although the general principle has been known for decades, chromatogram averaging is almost never used in current pharmaceutical research. In this study w...

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Hauptverfasser: Zawatzky, Kerstin (VerfasserIn) , Lin, Mingxiang (VerfasserIn) , Schafer, Wes (VerfasserIn) , Mao, Bing (VerfasserIn) , Trapp, Oliver (VerfasserIn) , Welch, Christopher J. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 22 August 2016
In: Journal of chromatography
Year: 2016, Jahrgang: 1465, Pages: 205-210
ISSN:1873-3778
DOI:10.1016/j.chroma.2016.08.047
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.chroma.2016.08.047
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0021967316311244
Volltext
Verfasserangaben:Kerstin Zawatzky, Mingxiang Lin, Wes Schafer, Bing Mao, Oliver Trapp, Christopher J. Welch

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