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Analytical performance of the Xpert MTB/XDR assay for tuberculosis and expanded resistance detection

In a manufacturer-independent laboratory validation study, the Xpert MTB/XDR® assay demonstrated equivalent limit of detection to Xpert MTB/RIF®, detected 100% of tested resistance mutations and showed some utility for resistance detection in strain mixtures. The Xpert MTB/XDR assay is a reliable, s...

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Main Authors: Georghiou, Sophia B. (Author) , Penn-Nicholson, Adam (Author) , de Vos, Margaretha (Author) , Macé, Aurélien (Author) , Syrmis, Melanie W (Author) , Jacob, Kevin (Author) , Mape, Alyanna (Author) , Parmar, Heta (Author) , Cao, Yuan (Author) , Coulter, Chris (Author) , Ruhwald, Morten (Author) , Pandey, Sushil K (Author) , Schumacher, Samuel G (Author) , Denkinger, Claudia M. (Author)
Format: Article (Journal)
Language:English
Published: 20 April 2021
In: Diagnostic microbiology and infectious disease
Year: 2021, Volume: 101, Issue: 1, Pages: 1-3
ISSN:1879-0070
DOI:10.1016/j.diagmicrobio.2021.115397
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.diagmicrobio.2021.115397
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0732889321000900
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Author Notes:Sophia B Georghiou, Adam Penn-Nicholson, Margaretha de Vos, Aurélien Macé, Melanie W Syrmis, Kevin Jacob, Alyanna Mape, Heta Parmar, Yuan Cao, Chris Coulter, Morten Ruhwald, Sushil K Pandey, Samuel G Schumacher, Claudia M Denkinger

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