Illuminating Plasmodium invasion by lattice-light-sheet microscopy
Plasmodium merozoites invade erythrocytes in a stepwise manner through ligand binding, calcium signaling, and membrane deformation. Using a recently developed light-sheet microscope, Geoghegan et al. investigated invasion with unprecedented temporal resolution. Their spectacular footage revealed rol...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
September 2021
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| In: |
Trends in parasitology
Year: 2021, Jahrgang: 37, Heft: 9, Pages: 777-779 |
| ISSN: | 1471-5007 |
| DOI: | 10.1016/j.pt.2021.07.008 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.pt.2021.07.008 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1471492221001732 
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| Verfasserangaben: | Markus Ganter and Friedrich Frischknecht |
| Zusammenfassung: | Plasmodium merozoites invade erythrocytes in a stepwise manner through ligand binding, calcium signaling, and membrane deformation. Using a recently developed light-sheet microscope, Geoghegan et al. investigated invasion with unprecedented temporal resolution. Their spectacular footage revealed roles for host cell cholesterol and pore formation at the parasite-host cell interface. |
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| Beschreibung: | Gesehen am 05.10.2021 |
| Beschreibung: | Online Resource |
| ISSN: | 1471-5007 |
| DOI: | 10.1016/j.pt.2021.07.008 |