Cardiovascular effects of (R)- and (S)-verapamil and racemic verapamil in humans: a placebo-controlled study
To characterise the comparative potency of optically pure (R)- and (S)-verapamil as regards negative dromotropic effects on atrioventricular (AV) node conduction and to compare the hemodynamic effects of single doses of the enantiomers in healthy volunteers.
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
4 July 2006
|
| In: |
European journal of clinical pharmacology
Year: 2006, Jahrgang: 62, Heft: 8, Pages: 613-619 |
| ISSN: | 1432-1041 |
| DOI: | 10.1007/s00228-006-0154-7 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00228-006-0154-7 Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007%2Fs00228-006-0154-7 
|
| Verfasserangaben: | Dagmar Busse, Silke Templin, Gerd Mikus, Matthias Schwab, Ute Hofmann, Michel Eichelbaum, Kari T. Kivistö |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1772741833 | ||
| 003 | DE-627 | ||
| 005 | 20230426091823.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 211007s2006 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00228-006-0154-7 |2 doi | |
| 035 | |a (DE-627)1772741833 | ||
| 035 | |a (DE-599)KXP1772741833 | ||
| 035 | |a (OCoLC)1341421548 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Busse, Dagmar |d 1965- |e VerfasserIn |0 (DE-588)11819190X |0 (DE-627)694749966 |0 (DE-576)291761445 |4 aut | |
| 245 | 1 | 0 | |a Cardiovascular effects of (R)- and (S)-verapamil and racemic verapamil in humans |b a placebo-controlled study |c Dagmar Busse, Silke Templin, Gerd Mikus, Matthias Schwab, Ute Hofmann, Michel Eichelbaum, Kari T. Kivistö |
| 264 | 1 | |c 4 July 2006 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 07.10.2021 | ||
| 520 | |a To characterise the comparative potency of optically pure (R)- and (S)-verapamil as regards negative dromotropic effects on atrioventricular (AV) node conduction and to compare the hemodynamic effects of single doses of the enantiomers in healthy volunteers. | ||
| 700 | 1 | |a Templin, Silke |e VerfasserIn |4 aut | |
| 700 | 1 | |a Mikus, Gerd |e VerfasserIn |0 (DE-588)110903137 |0 (DE-627)691097941 |0 (DE-576)336988710 |4 aut | |
| 700 | 1 | |a Schwab, Matthias |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hofmann, Ute |e VerfasserIn |4 aut | |
| 700 | 1 | |a Eichelbaum, Michel |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kivistö, Kari T. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European journal of clinical pharmacology |d Berlin : Springer, 1968 |g 62(2006), 8, Seite 613-619 |h Online-Ressource |w (DE-627)253722829 |w (DE-600)1459058-X |w (DE-576)072372613 |x 1432-1041 |7 nnas |a Cardiovascular effects of (R)- and (S)-verapamil and racemic verapamil in humans a placebo-controlled study |
| 773 | 1 | 8 | |g volume:62 |g year:2006 |g number:8 |g pages:613-619 |g extent:7 |a Cardiovascular effects of (R)- and (S)-verapamil and racemic verapamil in humans a placebo-controlled study |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00228-006-0154-7 |x Resolving-System |x Verlag |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://link.springer.com/article/10.1007%2Fs00228-006-0154-7 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20211007 | ||
| 993 | |a Article | ||
| 994 | |a 2006 | ||
| 998 | |g 110903137 |a Mikus, Gerd |m 110903137:Mikus, Gerd |d 910000 |d 910100 |d 50000 |e 910000PM110903137 |e 910100PM110903137 |e 50000PM110903137 |k 0/910000/ |k 1/910000/910100/ |k 0/50000/ |p 3 | ||
| 999 | |a KXP-PPN1772741833 |e 398509893X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"title":[{"title":"Cardiovascular effects of (R)- and (S)-verapamil and racemic verapamil in humans","subtitle":"a placebo-controlled study","title_sort":"Cardiovascular effects of (R)- and (S)-verapamil and racemic verapamil in humans"}],"person":[{"role":"aut","roleDisplay":"VerfasserIn","display":"Busse, Dagmar","given":"Dagmar","family":"Busse"},{"role":"aut","display":"Templin, Silke","roleDisplay":"VerfasserIn","given":"Silke","family":"Templin"},{"display":"Mikus, Gerd","roleDisplay":"VerfasserIn","role":"aut","family":"Mikus","given":"Gerd"},{"given":"Matthias","family":"Schwab","role":"aut","display":"Schwab, Matthias","roleDisplay":"VerfasserIn"},{"family":"Hofmann","given":"Ute","roleDisplay":"VerfasserIn","display":"Hofmann, Ute","role":"aut"},{"family":"Eichelbaum","given":"Michel","roleDisplay":"VerfasserIn","display":"Eichelbaum, Michel","role":"aut"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Kivistö, Kari T.","given":"Kari T.","family":"Kivistö"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 07.10.2021"],"recId":"1772741833","language":["eng"],"origin":[{"dateIssuedKey":"2006","dateIssuedDisp":"4 July 2006"}],"id":{"doi":["10.1007/s00228-006-0154-7"],"eki":["1772741833"]},"name":{"displayForm":["Dagmar Busse, Silke Templin, Gerd Mikus, Matthias Schwab, Ute Hofmann, Michel Eichelbaum, Kari T. Kivistö"]},"physDesc":[{"extent":"7 S."}],"relHost":[{"origin":[{"dateIssuedKey":"1968","publisher":"Springer","dateIssuedDisp":"1968-","publisherPlace":"Berlin ; Heidelberg ; New York"}],"id":{"eki":["253722829"],"zdb":["1459058-X"],"issn":["1432-1041"]},"name":{"displayForm":["organ of European Association for Clinical Pharmacology and Therapeutics (EACPT)"]},"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title":"European journal of clinical pharmacology","title_sort":"European journal of clinical pharmacology"}],"pubHistory":["1.1968/69 -"],"part":{"text":"62(2006), 8, Seite 613-619","volume":"62","extent":"7","year":"2006","pages":"613-619","issue":"8"},"titleAlt":[{"title":"Clinical pharmacology"},{"title":"EJCP"},{"title":"Pharmacologia clinica"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Cardiovascular effects of (R)- and (S)-verapamil and racemic verapamil in humans a placebo-controlled studyEuropean journal of clinical pharmacology","note":["Gesehen am 11.10.05"],"recId":"253722829","language":["eng"]}]} | ||
| SRT | |a BUSSEDAGMACARDIOVASC4200 | ||