Kidney re-transplantation in a child across the barrier of persisting angiotensin II type I receptor antibodies

Approximately 20% of antibody-mediated rejection (ABMR) episodes in the absence of donor-specific antibodies against human leucocyte antigens (HLA-DSA) in pediatric and adult kidney transplant recipients are associated with, and presumably caused by, antibodies against the angiotensin type 1 recepto...

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Bibliographische Detailangaben
Hauptverfasser: Gold, Annika (VerfasserIn) , Fichtner, Alexander (VerfasserIn) , Choukair, Daniela (VerfasserIn) , Schmitt, Claus P. (VerfasserIn) , Süsal, Caner (VerfasserIn) , Dragun, Duska (VerfasserIn) , Tönshoff, Burkhard (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2021
In: Pediatric nephrology
Year: 2021, Jahrgang: 36, Heft: 3, Pages: 725-729
ISSN:1432-198X
DOI:10.1007/s00467-020-04879-8
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00467-020-04879-8
Volltext
Verfasserangaben:Annika Gold, Alexander Fichtner, Daniela Choukair, Claus Peter Schmitt, Caner Süsal, Duska Dragun, Burkhard Tönshoff

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520 |a Approximately 20% of antibody-mediated rejection (ABMR) episodes in the absence of donor-specific antibodies against human leucocyte antigens (HLA-DSA) in pediatric and adult kidney transplant recipients are associated with, and presumably caused by, antibodies against the angiotensin type 1 receptor (AT1R-Ab). While the role of AT1R-Ab for ABMR and graft failure is increasingly recognized, there is little information available on the management of these patients for re-transplantation over the barrier of persisting AT1R-Ab. 
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