Scaling of embryonic patterning based on phase-gradient encoding
An ex vivo primary culture assay is developed that recapitulates mouse embryonic mesodermal patterning and segment formation; using this approach, it is shown that oscillating gene activity is central to maintain stable proportions during development.
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2013
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| In: |
Nature
Year: 2013, Jahrgang: 493, Heft: 7430, Pages: 101-105 |
| ISSN: | 1476-4687 |
| DOI: | 10.1038/nature11804 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nature11804 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nature11804 
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| Verfasserangaben: | Volker M. Lauschke, Charisios D. Tsiairis, Paul François & Alexander Aulehla |
| Zusammenfassung: | An ex vivo primary culture assay is developed that recapitulates mouse embryonic mesodermal patterning and segment formation; using this approach, it is shown that oscillating gene activity is central to maintain stable proportions during development. |
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| Beschreibung: | Published online 19 December 2012 Gesehen am 14.10.2021 |
| Beschreibung: | Online Resource |
| ISSN: | 1476-4687 |
| DOI: | 10.1038/nature11804 |