Selective Janus kinase inhibition preserves interferon-λ-mediated antiviral responses
TYK2 is required for efficient IFN-α/β signaling but dispensable for IFN-λ-mediated antiviral protection in epithelial cells.
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
14 May 2021
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| In: |
Science immunology
Year: 2021, Volume: 6, Issue: 59, Pages: 1-13 |
| ISSN: | 2470-9468 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://www.science.org/doi/abs/10.1126/sciimmunol.abd5318
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| Author Notes: | Daniel Schnepf, Stefania Crotta, Thiprampai Thamamongood, Megan Stanifer, Laura Polcik, Annette Ohnemus, Juliane Vier, Celia Jakob, Miriam Llorian, Hans Henrik Gad, Rune Hartmann, Birgit Strobl, Susanne Kirschnek, Steeve Boulant, Martin Schwemmle, Andreas Wack, Peter Staeheli |
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