Current opinion about hepatocellular carcinoma <10 mm

Background: Early detection of hepatocellular carcinoma (HCC) is important. Advances in liver imaging techniques have facilitated the detection of HCC at an early stage. However, there is a controversial discussion on how to diagnose very small HCC by imaging. The aim of the current review is to pre...

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Main Authors: Dong, Yi (Author) , Teufel, Andreas (Author) , Wang, Wen-Ping (Author) , Dietrich, Christoph F. (Author)
Format: Article (Journal)
Language:English
Published: 2021
In: Digestion
Year: 2021, Volume: 102, Issue: 3, Pages: 335-341
ISSN:1421-9867
DOI:10.1159/000507923
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000507923
Verlag, lizenzpflichtig, Volltext: https://www.karger.com/Article/FullText/507923
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Author Notes:Yi Dong, Andreas Teufel, Wen-Ping Wang, Christoph F. Dietrich

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520 |a Background: Early detection of hepatocellular carcinoma (HCC) is important. Advances in liver imaging techniques have facilitated the detection of HCC at an early stage. However, there is a controversial discussion on how to diagnose very small HCC by imaging. The aim of the current review is to present current published data on HCC ≤10 mm and discuss on how to best diagnose and treat such lesions. Summary: It is still challenging, however, to accurately characterize HCC <10 mm. The accuracy of contrast-enhanced ultrasound may be critical for early treatment decisions for cancer patients, particularly when CECT and/or CEMRI are inconclusive. Key Messages: The characterization of focal liver lesions <10 mm is frequently delayed until a follow-up imaging procedure demonstrates growth or stability. A repetition of ultrasound examination after 3 months for new nodules <1 cm should be recommended. 
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