Body mass index-adapted prospective coronary computed tomography angiography: determining the lowest limit for diagnostic purposes
Purpose - To investigate the value of 4 different protocols for prospectively triggered 256-slice coronary computed tomography angiography (coronary CTA). - Methods - Two hundred and ten patients underwent prospectively triggered coronary CTA for suspected or known coronary artery disease (CAD). Pat...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
14 January 2013
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| In: |
European journal of radiology
Year: 2013, Volume: 82, Issue: 5, Pages: e232-e239 |
| ISSN: | 1872-7727 |
| DOI: | 10.1016/j.ejrad.2012.12.013 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ejrad.2012.12.013 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0720048X12006419 
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| Author Notes: | Waldemar Hosch, Nina P. Hofmann, Dirk Mueller, Johannes Iwan, Gitsios Gitsioudis, Stefan Siebert, Evangelos Giannitsis, Hans U. Kauczor, Hugo A. Katus, Grigorios Korosoglou |
| Summary: | Purpose - To investigate the value of 4 different protocols for prospectively triggered 256-slice coronary computed tomography angiography (coronary CTA). - Methods - Two hundred and ten patients underwent prospectively triggered coronary CTA for suspected or known coronary artery disease (CAD). Patients with heart rate >75bps before the scan despite ß-blocker administration and with arrhythmia were excluded. From January to September 2010, 60 patients underwent coronary CTA using a non-tailored protocol (120kV; 200mAs) and served as our ‘control’ group. From September 2010 to April 2012, based on the body mass index (BMI) of the examined patients (BMI subgroups of <25; 25-28; 28-30, and ≥30kg/m2) current tube voltage and tube current were: (1) slightly, (2) moderately or (3) strongly reduced, resulting into the 3 following BMI-adapted acquisition groups: (1) a ‘standard’ (100/120kV; 100-200mAs; n=50), 2) a ‘low dose’ (100/120kV; 75-150mAs; n=50), and 3) an ‘ultra-low dose’ (100/120kV; 50-100mAs; n=50) protocol. - Results - Patients examined using the non-tailored protocol exhibited the highest radiation exposure (3.2±0.4mSv), followed by the standard (1.6±0.7mSv), low-dose (1.2±0.6mSv) and ultra-low dose protocol (0.7±0.3mSv) (radiation savings of 50%, 63% and 78% respectively). Overall image quality was similar with standard dose (1.9±0.6) and low-dose (2.0±0.5) compared to the non-tailored group (1.9±0.5) (p=NS for all). In the ultra-low dose group however, image quality was significant reduced (2.7±0.6), p<0.05 versus all other groups). - Conclusion - Using BMI-adapted low dose acquisitions image quality can be maintained with simultaneous radiation savings of ∼65% (dose of ∼1mSv). This appears to be the lower limit for diagnostic coronary CTA, whereas ultra-low dose acquisitions result in significant image degradation. |
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| Item Description: | Gesehen am 26.10.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1872-7727 |
| DOI: | 10.1016/j.ejrad.2012.12.013 |