Id1 and Id3 are regulated through matrix-assisted autocrine BMP signaling and represent therapeutic targets in melanoma

New treatment strategies for melanoma are urgently needed. This study shows that the extracellular matrix can stimulate autocrine bone morphogenetic protein signaling in melanoma cells, leading to up...

Bibliographic Details

Main Authors:	Sedlmeier, Georg (Author) , Al-Rawi, Vanessa (Author) , Buchert, Justyna (Author) , Yserentant, Klaus (Author) , Rothley, Melanie (Author) , Steshina, Anastasia (Author) , Gräßle, Simone (Author) , Wu, Ruolin (Author) , Hurrle, Thomas (Author) , Richer, Wilfrid (Author) , Decraene, Charles (Author) , Thiele, Wilko (Author) , Utikal, Jochen (Author) , Abuillan, Wasim (Author) , Tanaka, Motomu (Author) , Herten, Dirk-Peter (Author) , Hill, Caroline S. (Author) , Garvalov, Boyan K. (Author) , Jung, Nicole (Author) , Bräse, Stefan (Author) , Sleeman, Jonathan P. (Author)
Format:	Article (Journal)
Language:	English
Published:	2021
In:	Advanced therapeutics Year: 2021, Volume: 4, Issue: 2, Pages: 1-17
ISSN:	2366-3987
DOI:	10.1002/adtp.202000065
Online Access:	Verlag, kostenfrei, Volltext: https://doi.org/10.1002/adtp.202000065 Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/adtp.202000065
Author Notes:	Georg Sedlmeier, Vanessa Al-Rawi, Justyna Buchert, Klaus Yserentant, Melanie Rothley, Anastasia Steshina, Simone Gräßle, Ruo-Lin Wu, Thomas Hurrle, Wilfrid Richer, Charles Decraene, Wilko Thiele, Jochen Utikal, Wasim Abuillan, Motomu Tanaka, Dirk-Peter Herten, Caroline S. Hill, Boyan K. Garvalov, Nicole Jung, Stefan Bräse, and Jonathan P. Sleeman