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Rationale and design of a trial improving outcome of type 2 diabetics on hemodialysis

Rationale and design of a trial improving outcome of type 2 diabetics on hemodialysis. - Background - Non-insulin-dependent diabetes mellitus dialysis patients have the highest cardiovascular mortality known in any group of patients. Mixed dyslipidemia with moderately elevated low-density lipoprotei...

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Autori principali: Wanner, Christoph (Autore) , Krane, Vera (Autore) , Ruf, Günther (Autore) , März, Winfried (Autore) , Ritz, Eberhard (Autore)
Natura: Article (Journal)
Lingua:inglese
Pubblicazione: 1 July 1999
In: Kidney international
Year: 1999, Volume: 56, Pages: S222-S226
ISSN:1523-1755
DOI:10.1046/j.1523-1755.1999.07158.x
Accesso online:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1046/j.1523-1755.1999.07158.x
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0085253815466463
Testo
Note sull'autore:Christoph Wanner, Vera Krane, Günther Ruf, Winfried März, and Eberhard Ritz
Descrizione
Riassunto:Rationale and design of a trial improving outcome of type 2 diabetics on hemodialysis. - Background - Non-insulin-dependent diabetes mellitus dialysis patients have the highest cardiovascular mortality known in any group of patients. Mixed dyslipidemia with moderately elevated low-density lipoprotein (LDL) cholesterol and high levels of triglyceride-rich lipoproteins is common in this condition. It is not known, however, whether patients with type 2 diabetes on dialysis with this form of dyslipidemia derive benefit from lipid-lowering therapy. Recently, drugs have become available that potently lower triglyceride-rich, apoB-containing lipoproteins and thus permit testing of this issue. This is the first trial to address specifically the issue of whether the excessive cardiovascular mortality of patients with type 2 diabetes on dialysis can be lowered by statins.
Descrizione del documento:Gesehen am 28.10.2021
Descrizione fisica:Online Resource
ISSN:1523-1755
DOI:10.1046/j.1523-1755.1999.07158.x

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