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The COVID-19 pandemic and the need for an integrated and equitable approach: an international expert consensus paper

<p> <b>Background</b> One year after the declaration of the coronavirus disease 2019 (COVID-19) pandemic by the World Health Organization (WHO) and despite the implementation of mandatory physical barriers and social distancing, humanity remains challenged by a long-lasting and dev...

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Main Authors: Gerotziafas, Grigoris T. (Author) , Catalano, Mariella (Author) , Theodorou, Yiannis (Author) , Dreden, Patrick Van (Author) , Marechal, Vincent (Author) , Spyropoulos, Alex C. (Author) , Carter, Charles (Author) , Jabeen, Nusrat (Author) , Harenberg, Job (Author) , Elalamy, Ismail (Author) , Falanga, Anna (Author) , Fareed, Jawed (Author) , Agathaggelou, Petros (Author) , Antic, Darko (Author) , Antignani, Pier Luigi (Author) , Bosch, Manuel Monreal (Author) , Brenner, Benjamin (Author) , Chekhonin, Vladimir (Author) , Colgan, Mary-Paula (Author) , Dimopoulos, Meletios-Athanasios (Author) , Douketis, Jim (Author) , Elnazar, Essam Abo (Author) , Farkas, Katalin (Author) , Fazeli, Bahare (Author) , Fowkes, Gerry (Author) , Gu, Yongquan (Author) , Gligorov, Joseph (Author) , Ligocki, Mark A. (Author) , Indran, Tishya (Author) , Kannan, Meganathan (Author) , Kantarcioglu, Bulent (Author) , Kasse, Abdoul Aziz (Author) , Konstantinidis, Kostantinos (Author) , Leivano, Fabio (Author) , Lewis, Joseph (Author) , Makatsariya, Alexander (Author) , Mbaye, P. Massamba (Author) , Mahé, Isabelle (Author) , Panovska-Stavridis, Irina (Author) , Olinic, Dan-Mircea (Author) , Papageorgiou, Chryssa (Author) , Pecsvarady, Zsolt (Author) , Pillon, Sergio (Author) , Ramacciotti, Eduardo (Author) , Abdel-Razeq, Hikmat (Author) , Sabbah, Michele (Author) , Sassi, Mouna (Author) , Schernthaner, Gerit (Author) , Siddiqui, Fakiha (Author) , Shiomura, Jin (Author) , Slama-Schwok, Anny (Author) , Wautrecht, Jean Claude (Author) , Tafur, Alfonso (Author) , Taher, Ali (Author) , Klein-Wegel, Peter (Author) , Zhai, Zenguo (Author) , Zoubida, Tazi Mezalek (Author)
Format: Article (Journal)
Language:English
Published: 24. Juni 2021
In: Thrombosis and haemostasis
Year: 2021, Volume: 121, Issue: 8, Pages: 992-1007
ISSN:2567-689X
DOI:10.1055/a-1535-8807
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1055/a-1535-8807
Verlag, lizenzpflichtig, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/a-1535-8807
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Author Notes:Scientific Reviewer Committee

MARC

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500 |a Gesehen am 03.11.2021 
520 |a <p> <b>Background</b> One year after the declaration of the coronavirus disease 2019 (COVID-19) pandemic by the World Health Organization (WHO) and despite the implementation of mandatory physical barriers and social distancing, humanity remains challenged by a long-lasting and devastating public health crisis.</p> <p> <b>Management</b> Non-pharmacological interventions (NPIs) are efficient mitigation strategies. The success of these NPIs is dependent on the approval and commitment of the population. The launch of a mass vaccination program in many countries in late December 2020 with mRNA vaccines, adenovirus-based vaccines, and inactivated virus vaccines has generated hope for the end of the pandemic.</p> <p> <b>Current Issues</b> The continuous appearance of new pathogenic viral strains and the ability of vaccines to prevent infection and transmission raise important concerns as we try to achieve community immunity against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) and its variants. The need of a second and even third generation of vaccines has already been acknowledged by the WHO and governments.</p> <p> <b>Perspectives</b> There is a critical and urgent need for a balanced and integrated strategy for the management of the COVID-19 outbreaks organized on three axes: (1) <i>P</i>revention of the SARS-CoV-2 infection, (2) <i>Detection</i> and early diagnosis of patients at risk of disease worsening, and (3) <i>Anticipation</i> of medical care (PDA).</p> <p> <b>Conclusion</b> The “PDA strategy” integrated into state policy for the support and expansion of health systems and introduction of digital organizations (i.e., telemedicine, e-Health, artificial intelligence, and machine-learning technology) is of major importance for the preservation of citizens' health and life world-wide.</p> 
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