Quantitative magnetic resonance imaging and neuropsychological functions in dementia of the Alzheimer type
Background. The aim of the present study was to investigate neuropsychological functions in - dementia of the Alzheimer type (DAT) with respect to morphological changes that were revealed - by quantitative magnetic resonance imaging (MRI).Methods. Twenty patients with DAT (NINCDS-ADRDA criteria) a...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
01 January 1997
|
| In: |
Psychopharmacology
Year: 1997, Jahrgang: 27, Heft: 1, Pages: 221-229 |
| ISSN: | 1432-2072 |
| DOI: | 10.1017/S003329179600431X |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1017/S003329179600431X Verlag: https://www.cambridge.org/core/journals/psychological-medicine/article/quantitative-magnetic-resonance-imaging-and-neuropsychological-functions-in-dementia-of-the-alzheimer-type/E7360AEB4BE448594DDD25076A6F2CA0# 
|
| Verfasserangaben: | J. Pantel, J. Schröder, L.R. Schad, M. Friedlinger, M.V. Knopp, R. Schmitt, M. Geissler, S. Blüml, M. Essig, H. Sauer |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1777148596 | ||
| 003 | DE-627 | ||
| 005 | 20230426232542.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 211110s1997 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1017/S003329179600431X |2 doi | |
| 035 | |a (DE-627)1777148596 | ||
| 035 | |a (DE-599)KXP1777148596 | ||
| 035 | |a (OCoLC)1341423386 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Pantel, Johannes |d 1963- |e VerfasserIn |0 (DE-588)113067526 |0 (DE-627)588317039 |0 (DE-576)301323305 |4 aut | |
| 245 | 1 | 0 | |a Quantitative magnetic resonance imaging and neuropsychological functions in dementia of the Alzheimer type |c J. Pantel, J. Schröder, L.R. Schad, M. Friedlinger, M.V. Knopp, R. Schmitt, M. Geissler, S. Blüml, M. Essig, H. Sauer |
| 264 | 1 | |c 01 January 1997 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 10.11.2021 | ||
| 520 | |a Background. The aim of the present study was to investigate neuropsychological functions in - dementia of the Alzheimer type (DAT) with respect to morphological changes that were revealed - by quantitative magnetic resonance imaging (MRI).Methods. Twenty patients with DAT (NINCDS-ADRDA criteria) and 10 healthy age and sex - matched controls were included. The neuropsychological function was evaluated on a test - battery covering the severity of dementia, verbal and visual memory, concentration and - attention, language skills and general intelligence as well as activities of daily living. 3D MRI - sequences were acquired using a 1.5 T Siemens MAGNETOM. Whole brain volume, total - intracranial volume (TIV), volume of the frontal and temporal lobes and volumes of the - amygdalahippocampus complex (AHC) were assessed using the newly developed software NMRWin.Results. Apart from TIV all morphometric parameters differed significantly between the - diagnostic groups. AHC volumes discriminated best between the groups, with only a small overlap. - AHC atrophy exceeded generalized atrophy. These findings were confirmed when the data were - reanalysed after dividing the DAT patients into a mildly and moderately affected group. The - severity of dementia was significantly correlated with the volumes of the AHC and the volumes - of the temporal lobes bilaterally, but not with the whole brain volume and the volumes of the - frontal lobes.Conclusions. These results underline the important role of the temporal substructures for - aetiology and progression of DAT. They indicate that the volume of the AHC can be - monitored by MRI and may be used to follow up the disease process. | ||
| 700 | 1 | |a Schröder, Johannes |d 1957- |e VerfasserIn |0 (DE-588)138708517 |0 (DE-627)605263469 |0 (DE-576)308769848 |4 aut | |
| 700 | 1 | |a Schad, Lothar R. |d 1956- |e VerfasserIn |0 (DE-588)1028817630 |0 (DE-627)731640241 |0 (DE-576)376271221 |4 aut | |
| 700 | 1 | |a Friedlinger, Michael |e VerfasserIn |0 (DE-588)1225702704 |0 (DE-627)1745577920 |4 aut | |
| 700 | 1 | |a Knopp, Michael V. |e VerfasserIn |0 (DE-588)1076637442 |0 (DE-627)835139344 |0 (DE-576)167521527 |4 aut | |
| 700 | 1 | |a Schmitt, R. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Geissler, M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Blüml, S. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Essig, Marco |e VerfasserIn |0 (DE-588)1048464490 |0 (DE-627)780470605 |0 (DE-576)172458595 |4 aut | |
| 700 | 1 | |a Sauer, H. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Psychopharmacology |d Berlin : Springer, 1959 |g 27(1997), 1, Seite 221-229 |h Online-Ressource |w (DE-627)341342254 |w (DE-600)2066933-1 |w (DE-576)255486898 |x 1432-2072 |7 nnas |a Quantitative magnetic resonance imaging and neuropsychological functions in dementia of the Alzheimer type |
| 773 | 1 | 8 | |g volume:27 |g year:1997 |g number:1 |g pages:221-229 |g extent:9 |a Quantitative magnetic resonance imaging and neuropsychological functions in dementia of the Alzheimer type |
| 856 | 4 | 0 | |u https://doi.org/10.1017/S003329179600431X |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://www.cambridge.org/core/journals/psychological-medicine/article/quantitative-magnetic-resonance-imaging-and-neuropsychological-functions-in-dementia-of-the-alzheimer-type/E7360AEB4BE448594DDD25076A6F2CA0# |x Verlag |
| 951 | |a AR | ||
| 992 | |a 20211110 | ||
| 994 | |a 1997 | ||
| 998 | |g 1048464490 |a Essig, Marco |m 1048464490:Essig, Marco |d 50000 |e 50000PE1048464490 |k 0/50000/ |p 9 | ||
| 998 | |g 1076637442 |a Knopp, Michael V. |m 1076637442:Knopp, Michael V. |d 50000 |e 50000PK1076637442 |k 0/50000/ |p 5 | ||
| 998 | |g 1225702704 |a Friedlinger, Michael |m 1225702704:Friedlinger, Michael |p 4 | ||
| 998 | |g 1028817630 |a Schad, Lothar R. |m 1028817630:Schad, Lothar R. |d 60000 |e 60000PS1028817630 |k 0/60000/ |p 3 | ||
| 998 | |g 138708517 |a Schröder, Johannes |m 138708517:Schröder, Johannes |d 910000 |d 910600 |e 910000PS138708517 |e 910600PS138708517 |k 0/910000/ |k 1/910000/910600/ |p 2 | ||
| 998 | |g 113067526 |a Pantel, Johannes |m 113067526:Pantel, Johannes |d 910000 |d 910600 |e 910000PP113067526 |e 910600PP113067526 |k 0/910000/ |k 1/910000/910600/ |p 1 |x j | ||
| 999 | |a KXP-PPN1777148596 |e 400128152X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"note":["Gesehen am 10.11.2021"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"1777148596","language":["eng"],"person":[{"family":"Pantel","given":"Johannes","display":"Pantel, Johannes","roleDisplay":"VerfasserIn","role":"aut"},{"roleDisplay":"VerfasserIn","display":"Schröder, Johannes","role":"aut","family":"Schröder","given":"Johannes"},{"role":"aut","display":"Schad, Lothar R.","roleDisplay":"VerfasserIn","given":"Lothar R.","family":"Schad"},{"family":"Friedlinger","given":"Michael","roleDisplay":"VerfasserIn","display":"Friedlinger, Michael","role":"aut"},{"given":"Michael V.","family":"Knopp","role":"aut","display":"Knopp, Michael V.","roleDisplay":"VerfasserIn"},{"family":"Schmitt","given":"R.","roleDisplay":"VerfasserIn","display":"Schmitt, R.","role":"aut"},{"roleDisplay":"VerfasserIn","display":"Geissler, M.","role":"aut","family":"Geissler","given":"M."},{"family":"Blüml","given":"S.","roleDisplay":"VerfasserIn","display":"Blüml, S.","role":"aut"},{"family":"Essig","given":"Marco","roleDisplay":"VerfasserIn","display":"Essig, Marco","role":"aut"},{"roleDisplay":"VerfasserIn","display":"Sauer, H.","role":"aut","family":"Sauer","given":"H."}],"title":[{"title_sort":"Quantitative magnetic resonance imaging and neuropsychological functions in dementia of the Alzheimer type","title":"Quantitative magnetic resonance imaging and neuropsychological functions in dementia of the Alzheimer type"}],"physDesc":[{"extent":"9 S."}],"relHost":[{"note":["Gesehen am 14.07.06"],"disp":"Quantitative magnetic resonance imaging and neuropsychological functions in dementia of the Alzheimer typePsychopharmacology","type":{"media":"Online-Ressource","bibl":"periodical"},"recId":"341342254","language":["eng"],"pubHistory":["1.1959/60 -"],"part":{"pages":"221-229","issue":"1","year":"1997","extent":"9","volume":"27","text":"27(1997), 1, Seite 221-229"},"titleAlt":[{"title":"Psychopharmacologia"}],"title":[{"title":"Psychopharmacology","title_sort":"Psychopharmacology"}],"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"dateIssuedDisp":"1959-","publisher":"Springer ; Springer","dateIssuedKey":"1959","publisherPlace":"Berlin ; Heidelberg ; New York, NY ; Berlin ; Heidelberg [u.a.]"}],"id":{"issn":["1432-2072"],"eki":["341342254"],"zdb":["2066933-1"]}}],"name":{"displayForm":["J. Pantel, J. Schröder, L.R. Schad, M. Friedlinger, M.V. Knopp, R. Schmitt, M. Geissler, S. Blüml, M. Essig, H. Sauer"]},"origin":[{"dateIssuedDisp":"01 January 1997","dateIssuedKey":"1997"}],"id":{"doi":["10.1017/S003329179600431X"],"eki":["1777148596"]}} | ||
| SRT | |a PANTELJOHAQUANTITATI0119 | ||